Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43569 | 0.94 | TSHR (0.39) | APPTSHRSMN1; SMN2MAPTEPHX2 | |
| SCHEMBL43703 | 0.92 | TSHR (0.38) | APPTSHRSMN1; SMN2MAPTEPHX2 | |
| SCHEMBL43898 | 0.92 | TSHR (0.38) | APPTSHRSMN1; SMN2MAPTEPHX2 | |
| SCHEMBL43986 | 0.92 | TSHR (0.38) | APPTSHRSMN1; SMN2MAPTEPHX2 | |
| SCHEMBL44362 | 0.88 | PTGS1 (0.32) | APPTSHRSMN1; SMN2MAPTPTGS1 | |
| SCHEMBL5707749 | 0.77 | APP (0.41) | APPTSHRSMN1; SMN2MAPTEPHX2 | |
| SCHEMBL7859407 | 0.75 | APP (0.39) | APPTSHRSMN1; SMN2MAPTEPHX2 | |
| SCHEMBL20883310 | 0.74 | APP (0.36) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL7628967 | 0.74 | — | — | |
| SCHEMBL43269 | 0.74 | ACP1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708765-B1 | BIOCOMPATIBLE POLYMERIZATION ACCELERATORS | SURMODICS INC (US) | 2016-08-31 | — | — | EP | disclosed |
| US-8202833-B2 | Coating of polymer containing N-vinyl groups on cells, tissue | SURMODICS, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-7968614-B2 | Macromer composition including light activated initiator | SURMODICS, INC. (US) | 2011-06-28 | — | — | US | disclosed |
| EP-1893162-A2 | MACROMER COMPOSITION INCLUDING LIGHT ACTIVATED INITIATOR | SurModics, Inc. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006138542-A2 | MACROMER COMPOSITION INCLUDING LIGHT ACTIVATED INITIATOR | SURMODICS, INC. (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060287410-A1 | Macromer composition including light activated initiator | SURMODICS, INC. | 2006-12-21 | — | — | US | disclosed |
| US-20050112086-A1 | Biocompatible polymerization accelerators | SURMODICS, INC. | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050112086-A1 | Biocompatible polymerization accelerators | VCL, PCNA, CD38 | APP 3132/4885TSHR 4231/4885SMN1; SMN2 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.