SCHEMBL43269

SCHEMBL43269

C=CNC(=O)CS(=O)(=O)O

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 7/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44362 0.77 PTGS1 (0.32)
SCHEMBL9347058 0.76 ALOX15 (0.33)
SCHEMBL9056289 0.74
SCHEMBL44241 0.74 APP (0.37)
SCHEMBL43569 0.73 TSHR (0.39)
SCHEMBL43703 0.71 TSHR (0.38)
SCHEMBL43898 0.71 TSHR (0.38)
SCHEMBL43986 0.71 TSHR (0.38)
SCHEMBL7717817 0.70
SCHEMBL992848 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1708765-B1 BIOCOMPATIBLE POLYMERIZATION ACCELERATORS SURMODICS INC (US) 2016-08-31 EP disclosed
US-8202833-B2 Coating of polymer containing N-vinyl groups on cells, tissue SURMODICS, INC. (US) 2012-06-19 US disclosed
US-7968614-B2 Macromer composition including light activated initiator SURMODICS, INC. (US) 2011-06-28 US disclosed
EP-1893162-A2 MACROMER COMPOSITION INCLUDING LIGHT ACTIVATED INITIATOR SurModics, Inc. (US) 2008-03-05 EP disclosed
WO-2006138542-A2 MACROMER COMPOSITION INCLUDING LIGHT ACTIVATED INITIATOR SURMODICS, INC. (US) 2006-12-28 WO disclosed
US-20060287410-A1 Macromer composition including light activated initiator SURMODICS, INC. 2006-12-21 US disclosed
EP-1708765-A2 BIOCOMPATIBLE POLYMERIZATION ACCELERATORS SurModics, Inc. (US) 2006-10-11 EP disclosed
WO-2005054304-A2 BIOCOMPATIBLE POLYMERIZATION ACCELERATORS SURMODICS, INC. (US) 2005-06-16 WO disclosed
US-20050112086-A1 Biocompatible polymerization accelerators SURMODICS, INC. 2005-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050112086-A1 Biocompatible polymerization accelerators VCL, PCNA, CD38 ACP1 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.