Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293695 | 0.70 | — | — | |
| SCHEMBL10457412 | 0.70 | — | — | |
| SCHEMBL4882344 | 0.69 | NR1H2 (0.35) | NR1H2NR1H3 | |
| SCHEMBL10457411 | 0.66 | GABRA1 (0.37) | — | |
| SCHEMBL10457400 | 0.66 | — | — | |
| SCHEMBL28507381 | 0.66 | SMN1; SMN2 (0.44) | NR1H2NR1H3MLYCD | |
| SCHEMBL2140668 | 0.61 | — | — | |
| SCHEMBL28523241 | 0.60 | NR1H2 (0.36) | NR1H2NR1H3 | |
| SCHEMBL455408 | 0.60 | ESR1 (0.32) | — | |
| SCHEMBL2289393 | 0.59 | GABRA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4267920-B2 | — | — | 2009-05-27 | — | — | JP | claimed |
| JP-2004523542-A | — | — | 2004-08-05 | — | — | JP | claimed |
| EP-1377290-A2 | MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-01-07 | — | — | EP | claimed |
| WO-2002064136-A2 | MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-08-22 | — | — | WO | claimed |