Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.70 |
| ▸ | MAPT | P10636 | 9/20 | 0.70 |
| ▸ | MEN1 | O00255 | 9/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | NSD2 | O96028 | 1/20 | 0.66 |
| ▸ | ALPL | P05186 | 1/20 | 0.66 |
| ▸ | ALPI | P09923 | 1/20 | 0.66 |
| ▸ | ALPG | P10696 | 1/20 | 0.66 |
| ▸ | G6PD | P11413 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.66 |
| ▸ | APEX1 | P27695 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | BLM | P54132 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9742689 | 0.83 | MAPT (1.00) | KMT2AMAPTMEN1L3MBTL1TP53 | |
| SCHEMBL13856561 | 0.79 | MAPT (1.00) | KMT2AMAPTMEN1L3MBTL1TP53 | |
| SCHEMBL9742220 | 0.78 | MAPT (0.63) | KMT2AMAPTMEN1L3MBTL1TP53 | |
| SCHEMBL9744862 | 0.77 | MAPT (1.00) | KMT2AMAPTMEN1L3MBTL1TP53 | |
| SCHEMBL9744176 | 0.77 | MAPT (0.72) | KMT2AMAPTMEN1L3MBTL1TP53 | |
| SCHEMBL11598254 | 0.75 | MAPT (0.77) | KMT2AMAPTMEN1L3MBTL1TP53 | |
| SCHEMBL9738237 | 0.73 | MAPT (0.67) | KMT2AMAPTMEN1L3MBTL1TP53 | |
| SCHEMBL14391902 | 0.73 | MAPT (0.58) | KMT2AMAPTMEN1L3MBTL1TP53 | |
| SCHEMBL9743017 | 0.73 | KMT2A (0.65) | KMT2AMAPTMEN1L3MBTL1TP53 | |
| SCHEMBL5833790 | 0.72 | KMT2A (0.52) | KMT2AMAPTMEN1L3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009154747-A1 | PHARMACEUTICAL COMPOSITIONS | GENZYME CORPORATION (US) | 2009-12-23 | — | — | WO | disclosed |
| EP-0636247-A1 | METHOD AND COMPOSITION FOR REDUCING THE EFFECTS OF ENDOGENOUS ALKALINE PHOSPHATASE | DADE INTERNATIONAL INC. (US) | 1995-02-01 | — | — | EP | disclosed |
| WO-1994019691-A1 | METHOD AND COMPOSITION FOR REDUCING THE EFFECTS OF ENDOGENOUS ALKALINE PHOSPHATASE | BAXTER DIAGNOSTICS INC. (US) | 1994-09-01 | — | — | WO | disclosed |