Bicarbonate

Bicarbonate

SCHEMBL4424344

CO.O=C(O)O.[KH]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL29519185 0.94
Bicarbonate SCHEMBL4447985 0.94
Bicarbonate SCHEMBL27603254 0.94 CA1 (0.71)
Bicarbonate SCHEMBL5068363 0.88
Bicarbonate SCHEMBL28623473 0.88 CA1 (0.62)
Bicarbonate SCHEMBL28099673 0.88
Bicarbonate SCHEMBL13519489 0.88
Bicarbonate SCHEMBL10477709 0.88
Bicarbonate SCHEMBL7607307 0.88
Bicarbonate SCHEMBL28042547 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117720436-A Organic crystal with thermal phase transition induced mechanical behavior and fluorescence enhancement and preparation method and application thereof 广西民族大学 2024-03-19 CN claimed
CN-115490679-A D-pi-A structure tri-substituted olefin with high affinity with alpha-synuclein, and preparation method and application thereof 北京核素医药科技有限公司 2022-12-20 CN claimed
CN-110804175-B Antibacterial polyamino acid derivative or copolymer with alternating structure and preparation method thereof 中国科学院理化技术研究所 2021-05-14 CN claimed
CN-111253457-B Method for preparing 16alpha-hydroxy prednisolone 浙江神洲药业有限公司 2021-03-19 CN claimed
CN-111253457-A Method for preparing 16 α -hydroxy prednisolone 浙江神洲药业有限公司 2020-06-09 CN claimed
CN-110804175-A Antibacterial polyamino acid derivative or copolymer with alternating structure and preparation method thereof 中国科学院理化技术研究所 2020-02-18 CN claimed
CN-107602376-A The synthetic method of Neil before one koji arranges 上海泰坦科技股份有限公司 2018-01-19 CN claimed
CN-107325809-A A kind of and A β plaque block has fluorescent chemicals and the preparation and application of affinity 华南理工大学 2017-11-07 CN claimed
CN-117720436-A Organic crystal with thermal phase transition induced mechanical behavior and fluorescence enhancement and preparation method and application thereof 广西民族大学 2024-03-19 CN disclosed
WO-2023113038-A1 OLIGONUCLEOTIDE PRODUCTION METHOD リードファーマ株式会社 2023-06-22 WO disclosed
CN-115490679-A D-pi-A structure tri-substituted olefin with high affinity with alpha-synuclein, and preparation method and application thereof 北京核素医药科技有限公司 2022-12-20 CN disclosed
CN-110804175-B Antibacterial polyamino acid derivative or copolymer with alternating structure and preparation method thereof 中国科学院理化技术研究所 2021-05-14 CN disclosed
CN-111253457-B Method for preparing 16alpha-hydroxy prednisolone 浙江神洲药业有限公司 2021-03-19 CN disclosed
CN-111253457-A Method for preparing 16 α -hydroxy prednisolone 浙江神洲药业有限公司 2020-06-09 CN disclosed
CN-101827525-A Kinase inhibitor compounds XCOVERY INC 2010-09-08 CN disclosed
EP-2086945-A2 NOVEL PROCESS FOR THE PREPARATION OF STATINS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF Satyanarayana Reddy, Manne (IN) 2009-08-12 EP disclosed
WO-2008044243-A9 NOVEL PROCESS FOR THE PREPARATION OF STATINS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF SATYANARAYANA REDDY MANNE (IN) 2008-11-13 WO disclosed
WO-2008044243-A2 NOVEL PROCESS FOR THE PREPARATION OF STATINS AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF SATYANARAYANA REDDY MANNE (IN) 2008-04-17 WO disclosed
CN-1201392-A Pentacyclic compounds, intermediates, processes, compositions and methods LILLY CO ELI (US) 1998-12-09 CN disclosed
US-4692554-A MONOMER FOR POLYAMIDES AND POLYIMIDES, FROM HALOBENZENES AND AMINOPHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1987-09-08 US disclosed