Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5068363 | 1.00 | — | — | |
| Bicarbonate SCHEMBL4447985 | 0.94 | — | — | |
| Bicarbonate SCHEMBL29519185 | 0.94 | — | — | |
| Bicarbonate SCHEMBL27603254 | 0.94 | CA1 (0.71) | — | |
| Bicarbonate SCHEMBL28358443 | 0.88 | CA1 (0.62) | — | |
| Bicarbonate SCHEMBL10477709 | 0.88 | — | — | |
| Bicarbonate SCHEMBL28623473 | 0.88 | CA1 (0.62) | — | |
| Bicarbonate SCHEMBL4424344 | 0.88 | — | — | |
| Bicarbonate SCHEMBL13519489 | 0.88 | — | — | |
| Bicarbonate SCHEMBL28099673 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118258919-A | Method for detecting farnesyl pyrophosphate and geranylgeranyl pyrophosphate in biological sample | 华南农业大学 | 2024-06-28 | — | — | CN | claimed |
| CN-111024843-B | Combined marker for diagnosing Parkinson's disease and detection kit | 大连医科大学附属第一医院 | 2022-06-21 | — | — | CN | claimed |
| CN-112198233-B | Combined marker and kit for diagnosis of retinopathy in diabetic patients | DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2021-08-31 | — | — | CN | claimed |
| CN-112198233-A | Combined marker and kit for diagnosis of retinopathy in diabetic patients | 中国科学院大连化学物理研究所 | 2021-01-08 | — | — | CN | claimed |
| CN-104777242-B | Associating mark, test kit and system for diagnosis of polycystic ovary syndrome | 中国科学院大连化学物理研究所 | 2016-08-17 | — | — | CN | claimed |
| CN-104777242-A | Combined markers, kit and system for diagnosis of polycystic ovarian syndrome | DALIAN CHEMICAL PHYSICS INST | 2015-07-15 | — | — | CN | claimed |
| CN-114887456-B | Ammonium bicarbonate crystallization prevention system for low-temperature methanol washing process | 蒲城清洁能源化工有限责任公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-118258919-A | Method for detecting farnesyl pyrophosphate and geranylgeranyl pyrophosphate in biological sample | 华南农业大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-111024843-B | Combined marker for diagnosing Parkinson's disease and detection kit | 大连医科大学附属第一医院 | 2022-06-21 | — | — | CN | disclosed |
| US-20220002265-A1 | RHO KINASE INHIBITOR, METHOD FOR PREPARING SAME AND USES THEREOF | BEIJING INCREASE INNOVATIVE DRUG CO., LTD (CN) | 2022-01-06 | — | — | US | disclosed |
| CN-113777178-A | Proteomics background library based on mixed spectrogram library, and construction method and application thereof | 复旦大学 | 2021-12-10 | — | — | CN | disclosed |
| EP-3878846-A1 | RHO KINASE INHIBITOR, METHOD FOR PREPARING SAME AND USES THEREOF | Beijing Increase Innovative Drug Co., Ltd. (CN) | 2021-09-15 | — | — | EP | disclosed |
| CN-112198233-B | Combined marker and kit for diagnosis of retinopathy in diabetic patients | DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2021-08-31 | — | — | CN | disclosed |
| CN-104364658-B | For the method for diagnosing chronic valve disease | 雀巢产品技术援助有限公司 | 2017-06-30 | — | — | CN | disclosed |
| CN-104777242-B | Associating mark, test kit and system for diagnosis of polycystic ovary syndrome | 中国科学院大连化学物理研究所 | 2016-08-17 | — | — | CN | disclosed |
| CN-104777242-A | Combined markers, kit and system for diagnosis of polycystic ovarian syndrome | DALIAN CHEMICAL PHYSICS INST | 2015-07-15 | — | — | CN | disclosed |
| CN-103529139-B | Method for analyzing metabolism difference of transgenic rice by using natural variation | UNIV SHANGHAI JIAOTONG | 2015-03-11 | — | — | CN | disclosed |
| CN-103529139-A | Method for analyzing metabolism difference of transgenic rice by using natural variation | UNIV SHANGHAI JIAOTONG | 2014-01-22 | — | — | CN | disclosed |
| WO-2002081630-A2 | USE OF SEMENOGELIN IN THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF CANCER | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2002-10-17 | — | — | WO | disclosed |
| US-6342765-B1 | COMPOUNDS THAT INHIBIT FARNESYLATION OF MUTANT RAS GENE PRODUCTS; TREATING DISEASES, ESPECIALLY CANCER, WHICH ARE MEDIATED THROUGH FARNESYLATION OF RAS | ASTRAZENECA UK LIMITED (GB) | 2002-01-29 | — | — | US | disclosed |