SCHEMBL4424751

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4429089	0.91	HDAC1 (0.58)	HDAC1HDAC3HDAC4HDAC7HDAC2
	SCHEMBL4433179	0.84	HDAC1 (0.71)	HDAC1HDAC3HDAC4HDAC7HDAC2
	SCHEMBL4425828	0.80	HDAC1 (0.67)	HDAC1HDAC3HDAC4HDAC7HDAC2
	SCHEMBL5445354	0.79	ALDH1A1 (0.47)	HDAC1HDAC3HDAC4HDAC7HDAC2
	SCHEMBL4928157	0.77	HDAC1 (0.56)	HDAC1HDAC3HDAC4HDAC7HDAC2
	SCHEMBL18997461	0.75	HPGD (0.67)	HDAC1HDAC3HDAC4HDAC7HDAC2
	SCHEMBL4424527	0.75	HDAC1 (0.65)	HDAC1HDAC3HDAC4HDAC7HDAC2
	SCHEMBL8289901	0.75	HDAC1 (0.76)	HDAC1HDAC3HDAC4HDAC7HDAC2
	SCHEMBL3608241	0.74	IKBKB (0.55)	—
	SCHEMBL8290074	0.74	ACKR3 (0.60)	HDAC1ACKR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.