Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL386358 | 0.89 | GPR119 (0.59) | GPR119CYP2C9KCNH2 | |
| SCHEMBL5274347 | 0.88 | GPR119 (0.60) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390135 | 0.83 | GPR119 (0.54) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390411 | 0.79 | GPR119 (0.58) | GPR119 | |
| SCHEMBL388955 | 0.78 | GPR119 (0.75) | GPR119CYP2C9KCNH2 | |
| SCHEMBL4328393 | 0.77 | GPR119 (0.48) | GPR119CYP2C9KCNH2 | |
| SCHEMBL386087 | 0.77 | GPR119 (0.45) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390700 | 0.76 | GPR119 (0.57) | GPR119CYP2C9KCNH2 | |
| SCHEMBL389390 | 0.74 | GPR119 (0.80) | GPR119CYP2C9KCNH2 | |
| SCHEMBL390832 | 0.74 | GPR119 (0.65) | GPR119CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758565-B2 | Method of identifying GLP-1 secretagogues | ARENA PHARM INC (US) | 2012-11-14 | — | — | EP | disclosed |
| EP-1758565-B1 | Method of identifying GLP-1 secretagogues | ARENA PHARM INC (US) | 2009-05-13 | — | — | EP | disclosed |