Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 13/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3169132 | 0.85 | EPHX2 (0.40) | CASREPHX2GLP1RGCGRPTGDR2 | |
| SCHEMBL3166382 | 0.83 | PTGDR2 (0.39) | CASREPHX2GLP1RGCGRPTGDR2 | |
| SCHEMBL12678724 | 0.82 | CASR (0.43) | CASREPHX2GLP1RGCGRPTGDR2 | |
| SCHEMBL4425054 | 0.82 | GPR52 (0.36) | EPHX2GPR52 | |
| SCHEMBL12678723 | 0.80 | CASR (0.36) | CASREPHX2GLP1RGCGRPTGDR2 | |
| SCHEMBL3169588 | 0.75 | EPHX2 (0.41) | CASREPHX2GLP1RGCGRPTGDR2 | |
| SCHEMBL3168994 | 0.71 | HDAC1 (0.47) | CASREPHX2GLP1RGCGRPTGDR2 | |
| SCHEMBL3159511 | 0.70 | EPHX2 (0.51) | CASREPHX2GLP1RGCGRPTGDR2 | |
| SCHEMBL3173586 | 0.70 | MEN1 (0.49) | EPHX2 | |
| SCHEMBL3175180 | 0.69 | CREBBP (0.46) | CASREPHX2GLP1RGCGRPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094662-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008072784-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2008-06-19 | — | — | WO | disclosed |