Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.76 |
| ▸ | ITGA2B | P08514 | 17/20 | 0.76 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4415017 | 0.99 | ITGB3 (0.76) | ITGB3ITGA2BMAOBMAOA | |
| SCHEMBL4424359 | 0.97 | ITGB3 (0.75) | ITGB3ITGA2BMAOBMAOA | |
| SCHEMBL4422784 | 0.93 | ITGB3 (0.75) | ITGB3ITGA2BMAOBMAOA | |
| SCHEMBL4422725 | 0.91 | ITGB3 (0.77) | ITGB3ITGA2BMAOBMAOA | |
| SCHEMBL4420198 | 0.90 | ITGB3 (0.76) | ITGB3ITGA2BMAOBMAOA | |
| SCHEMBL4417756 | 0.90 | ITGB3 (0.62) | ITGB3ITGA2BMAOBMAOA | |
| SCHEMBL4420569 | 0.90 | ITGB3 (0.74) | ITGB3ITGA2BMAOBMAOA | |
| SCHEMBL4427043 | 0.89 | ITGB3 (0.62) | ITGB3ITGA2BMAOBMAOA | |
| SCHEMBL4424269 | 0.87 | ITGB3 (0.61) | ITGB3ITGA2BMAOBMAOA | |
| SCHEMBL4418712 | 0.83 | ITGB3 (0.60) | ITGB3ITGA2BMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501804-B1 | ISOQUINOLINE DERIVATIVES MAO-B INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-08-26 | — | — | EP | claimed |