⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8841986 | 0.91 | — | — | |
| SCHEMBL3543870 | 0.88 | — | — | |
| SCHEMBL3065604 | 0.71 | — | — | |
| SCHEMBL3058967 | 0.63 | — | — | |
| SCHEMBL8842304 | 0.59 | — | — | |
| SCHEMBL8842361 | 0.59 | — | — | |
| SCHEMBL2670377 | 0.58 | — | — | |
| SCHEMBL28134797 | 0.54 | — | — | |
| SCHEMBL25334383 | 0.53 | — | — | |
| SCHEMBL2451 | 0.48 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8253 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024131776-A1 | BUFALIN DERIVATIVE AND PREPARATION METHOD THEREFOR, COMPOSITION, PREPARATION, AND APPLICATION | 上海邈基生物科技有限公司 | 2024-06-27 | — | — | WO | claimed |
| EP-4389130-A1 | APPLICATION OF STEROID COMPOUND IN PREPARATION OF DRUG FOR PREVENTING AND/OR TREATING EYE FLOATERS | Guangzhou Ocusun Ophthalmic Biotechnology Co., Ltd. (CN) | 2024-06-26 | — | — | EP | claimed |
| EP-3568390-B1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INST (US) | 2024-03-06 | — | — | EP | claimed |
| WO-2024017315-A1 | USE OF STEROID COMPOUND IN PREPARATION OF MEDICAMENT FOR PREVENTING AND/OR TREATING OPHTHALMIC DISEASES | 广州润尔眼科生物科技有限公司 | 2024-01-25 | — | — | WO | claimed |
| WO-2023222116-A1 | USE OF STEROID COMPOUND | 广州润尔眼科生物科技有限公司 | 2023-11-23 | — | — | WO | claimed |
| US-11806337-B2 | Small molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and uses thereof | Sanford Burnham Prebys Medical Discovery Institute (US) | 2023-11-07 | — | — | US | claimed |
| WO-2023198192-A1 | USE OF STEROID COMPOUND IN PREPARING DRUGS FOR PREVENTING AND/OR TREATING PRESBYOPIA | 广州润尔眼科生物科技有限公司 | 2023-10-19 | — | — | WO | claimed |
| WO-2023061492-A1 | 2-OXO-3-AZABICYCLO[3.1.0]HEXANE DERIVATIVE | 华领医药技术（上海）有限公司 | 2023-04-20 | — | — | WO | claimed |
| US-20230116770-A1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute | 2023-04-13 | — | — | US | claimed |
| US-20210171467-A1 | REDOX SUBSTRATES FOR LEUKOCYTE ESTERASE | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-06-10 | — | — | US | claimed |
| WO-2002083642-A1 | COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-10-24 | — | — | WO | claimed |
| EP-1232150-A1 | UREA DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2002-08-21 | — | — | EP | claimed |
| US-20020055507-A1 | Compounds useful as anti-inflammatory agents | BETAGERI RAJASHEHAR (US) | 2002-05-09 | — | — | US | claimed |
| US-20020032195-A1 | Compounds useful as anti-inflammatory agents | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-03-14 | — | — | US | claimed |
| EP-1165516-A2 | HETEROCYCLIC UREA AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2001036403-A1 | UREA DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-05-25 | — | — | WO | claimed |
| WO-2000055139-A2 | HETEROCYCLIC UREA AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | claimed |
| US-H563-H | Use of sulfur-containing compounds for controlling plant parasitic nematodes | RHONE POULENC NEDERLANDS B.V. (NL) | 1989-01-03 | — | — | US | claimed |
| US-4551472-A | Unsymmetrical bis-carbamate compounds | UNION CARBIDE CORPORATION (US) | 1985-11-05 | — | — | US | claimed |
| US-4169894-A | INSECTICIDES, MITICIDES, NEMATOCIDES | UNION CARBIDE CORPORATION (US) | 1979-10-02 | — | — | US | claimed |