Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA6 | P23280 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA3 | P07451 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL28256231 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL28255110 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL3898035 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL5088799 | 0.93 | MAPT (0.46) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL28924405 | 0.91 | NFKB1 (0.50) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL30253568 | 0.91 | — | — | |
| Ethylenediamine SCHEMBL3083 | 0.91 | — | — | |
| Ethylenediamine SCHEMBL7085968 | 0.91 | NFKB1 (0.50) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL37647 | 0.91 | — | — | |
| Ethylenediamine SCHEMBL23633140 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700546-B2 | Trivalent chromium compounds, compositions and methods of use | INTERHEALTH NUTRACEUTICALS, INC. (US) | 2017-07-11 | — | — | US | disclosed |
| US-20160354353-A9 | TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE | LONZA CONSUMER HEALTH INC. | 2016-12-08 | — | — | US | disclosed |
| US-20150306083-A1 | TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE | INTERHEALTH NUTRACEUTICALS INC (US) | 2015-10-29 | — | — | US | disclosed |
| CN-102134529-B | Cleaning solution composition for cleaning solar cell substrate | CHI MEI CORP | 2012-11-28 | — | — | CN | disclosed |
| CN-102134529-A | Cleaning solution composition for cleaning solar cell substrate | CHI MEI IND CO LTD | 2011-07-27 | — | — | CN | disclosed |
| US-20090092560-A1 | TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE | INTERHEALTH NUTRACEUTICALS, INC. (US) | 2009-04-09 | — | — | US | disclosed |
| EP-2012770-A2 | TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Interhealth Nutraceuticals, Inc. (US) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007121312-A9 | TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE | INTERHEALTH NUTRACEUTICALS INC (US) | 2008-07-17 | — | — | WO | disclosed |
| WO-2007121312-A2 | TRIVALENT CHROMIUM COMPOUNDS, COMPOSITIONS AND METHODS OF USE | INTERHEALTH NUTRACEUTICALS, INC. (US) | 2007-10-25 | — | — | WO | disclosed |
| US-3962193-A | PROCESS FOR PREPARING LINEAR POLYESTERS IN THE PRESENCE OF METALLIC AMINO COMPOUNDS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-06-08 | — | — | US | disclosed |