Citronellal

Citronellal

SCHEMBL442629

CC(=O)O.CC(C)=CCCC(C)CC=O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Citronellal. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TSHR P16473 1/20 0.47
USP2 O75604 1/20 0.43
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41
GGPS1 O95749 2/20 0.39
FDPS P14324 2/20 0.39
GLA P06280 2/20 0.39
HPGD P15428 1/20 0.39
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(-)-Citronellal SCHEMBL726161 0.94 ALOX15 (0.57) ALOX15ALDH1A1TSHRUSP2GGPS1
Citronellal SCHEMBL1864131 0.94 ALOX15 (0.57) ALOX15ALDH1A1TSHRUSP2GGPS1
Citronellal SCHEMBL29275 0.94 ALOX15 (0.57) ALOX15ALDH1A1TSHRUSP2GGPS1
Citronellal SCHEMBL457495 0.94 ALOX15 (0.57) ALOX15ALDH1A1TSHRUSP2GGPS1
Citronellal SCHEMBL27550931 0.93 ALOX15 (0.49) ALOX15ALDH1A1TSHRUSP2FNTA
Citronellal SCHEMBL25260936 0.92 ALOX15 (0.55) ALOX15ALDH1A1TSHRUSP2GGPS1
Citronellal SCHEMBL10553397 0.92 ALOX15 (0.55) ALOX15ALDH1A1TSHRUSP2GGPS1
Citronellal SCHEMBL28427452 0.92 ALOX15 (0.55) ALOX15ALDH1A1TSHRUSP2GGPS1
Citronellal SCHEMBL3310337 0.92 ALOX15 (0.55) ALOX15ALDH1A1TSHRUSP2GGPS1
Citronellal SCHEMBL1179118 0.90 ALOX15 (0.53) ALOX15ALDH1A1TSHRUSP2GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106367286-A Vinegar and preparation method thereof 全椒先奇医药科技有限公司 2017-02-01 CN claimed
US-20130209371-A1 Germ Solve Candle WILLIS MARK ANTHONY (US) 2013-08-15 US claimed
CN-118995350-A Soluble nanocellulose sheet 伯克利医疗资源股份有限公司 2024-11-22 CN disclosed
US-20240110124-A1 TERPENE-BASED COMPOSITIONS, METHODOLGIES FOR CREATION AND PRODUCTS THEREBY SCIENTIFIC HOLDINGS, LLC (US) 2024-04-04 US disclosed
US-20240110125-A1 TERPENE-BASED COMPOSITIONS, PROCESSES, METHODOLOGIES FOR CREATION AND PRODUCTS THEREBY SCIENTIFIC HOLDINGS, LLC (US) 2024-04-04 US disclosed
CN-106367286-A Vinegar and preparation method thereof 全椒先奇医药科技有限公司 2017-02-01 CN disclosed
CN-106367286-A Vinegar and preparation method thereof 全椒先奇医药科技有限公司 2017-02-01 CN disclosed
US-20150216164-A1 SPATIAL INHIBITORS, DETERRENTS AND REPELLENTS FOR MOSQUITOES AND MIDGES BEDOUKIAN RESEARCH, INC. 2015-08-06 US disclosed
US-20150104348-A1 Pet Deodorizing Composition THE IAMS COMPANY (US) 2015-04-16 US disclosed
US-8852224-B2 Therapeutic delivery system WINTER BREATH LLC 2014-10-07 US disclosed
US-20140155843-A1 THERAPEUTIC DELIVERY SYSTEM WINTER BREATH LLC 2014-06-05 US disclosed
US-20140066976-A1 THERAPEUTIC DELIVERY SYSTEM CRONK PETER J (US) 2014-03-06 US disclosed
US-20130309299-A1 THERAPEUTIC DELIVERY SYSTEM CRONK PETER J (US) 2013-11-21 US disclosed
US-20130209371-A1 Germ Solve Candle WILLIS MARK ANTHONY (US) 2013-08-15 US disclosed
US-8188030-B2 Fabric softener compositions and methods of manufacture thereof SEGETIS, INC. (US) 2012-05-29 US disclosed
US-20120065113-A1 FABRIC SOFTENER COMPOSITIONS AND METHODS OF MANUFACTURE THEREOF SEGETIS, INC. (US) 2012-03-15 US disclosed
US-7655613-B2 Solubilizing systems for flavors and fragrances FIRMENICH SA (CH) 2010-02-02 US disclosed
US-20070161526-A1 SOLUBILIZING SYSTEMS FOR FLAVORS AND FRAGRANCES FIRMENICH SA (CH) 2007-07-12 US disclosed