SCHEMBL442633

SCHEMBL442633

CC1=CC(=C2C=C(C(C)(C)C)C(=O)C(C(C)(C)C)=C2)C=C(C)C1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 4/20 0.43
ALDH1A1 P00352 3/20 0.43
MAPT P10636 3/20 0.43
PKM P14618 2/20 0.43
HPGD P15428 2/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
MPI P34949 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
MCL1 Q07820 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.36
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.33
GPR35 Q9HC97 1/20 0.33
POLB P06746 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
MEN1 O00255 1/20 0.30
PLIN1 O60240 1/20 0.30
NR1I2 O75469 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12677688 0.93 ATM (0.45) ATMALDH1A1MAPTPKMHPGD
SCHEMBL14673579 0.93 ATM (0.45) ATMALDH1A1MAPTPKMHPGD
SCHEMBL4751533 0.93 ATM (0.45) ATMALDH1A1MAPTPKMHPGD
SCHEMBL16362005 0.90 ALDH1A1 (0.37) ATMALDH1A1MAPTPKMHPGD
SCHEMBL359232 0.88 ATM (0.52) ATMALDH1A1MAPTPKMHPGD
SCHEMBL12767612 0.82 ALDH1A1 (0.41) ATMALDH1A1MAPTPKMHPGD
SCHEMBL2741115 0.80 ALDH1A1 (0.40) ATMALDH1A1MAPTPKMHPGD
SCHEMBL14081321 0.78 ATM (0.48) ATMALDH1A1MAPTPKMHPGD
SCHEMBL13010088 0.77 SMN1; SMN2 (0.44) ATMALDH1A1MAPTPKMHPGD
SCHEMBL12315144 0.77 ATM (0.41) ATMALDH1A1MAPTPKMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116300351-A Positive-charging double-layer organic photoconductor drum and preparation method thereof 中船重工汉光科技股份有限公司 2023-06-23 CN claimed
WO-2023109968-A2 SYNTHESIS METHOD FOR FINERENONE AND INTERMEDIATE THEREOF 上海鼎雅药物化学科技有限公司 2023-06-22 WO claimed
CN-114149427-A Synthesis method of non-neferitone and intermediate thereof 上海鼎雅药物化学科技有限公司 2022-03-08 CN claimed
US-20230296995-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-09-21 US disclosed
US-20230273535-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-31 US disclosed
US-20230273535-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-31 US disclosed
US-20230259046-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, CARTRIDGE USING SAME, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-17 US disclosed
US-20230259046-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, CARTRIDGE USING SAME, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-17 US disclosed
CN-116300351-A Positive-charging double-layer organic photoconductor drum and preparation method thereof 中船重工汉光科技股份有限公司 2023-06-23 CN disclosed
WO-2023109968-A2 SYNTHESIS METHOD FOR FINERENONE AND INTERMEDIATE THEREOF 上海鼎雅药物化学科技有限公司 2023-06-22 WO disclosed
US-11640120-B2 Image forming apparatus and image forming method KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2023-05-02 US disclosed
US-7217482-B2 Electrophotographic photoreceptor containing a chelate compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-05-15 US disclosed
US-20070059619-A1 Electrophotographic photoconductor, image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed
US-7183009-B2 Organic electroluminescent element FUJI XEROX CO., LTD. (JP) 2007-02-27 US disclosed
US-7175958-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
US-7175958-B2 Electrophotographic photoconductor, process for forming an image, image forming apparatus and process cartridge for the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
EP-1093025-B1 Titanyl phthalocyanine crystal and production method of the same and electrophotosensitive material KYOCERA MITA CORP (JP) 2007-01-31 EP disclosed
US-7157196-B2 Containing charge generating compound and charge transfer compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-01-02 US disclosed
US-7157196-B2 Containing charge generating compound and charge transfer compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-01-02 US disclosed
US-6395439-B1 PHOTOCONDUCTIVITY KYOCERA MITA CORPORATION (JP) 2002-05-28 US disclosed