Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25812653 | 1.00 | CA12 (0.38) | CA12CA14CA2DGAT1CYP2D6 | |
| SCHEMBL14666479 | 1.00 | CA12 (0.38) | CA12CA14CA2DGAT1CYP2D6 | |
| Hydrochloric Acid SCHEMBL14656788 | 0.98 | CA12 (0.37) | CA12CA14CA2DGAT1CYP2D6 | |
| Hydrochloric Acid SCHEMBL12501616 | 0.98 | CA12 (0.37) | CA12CA14CA2DGAT1CYP2D6 | |
| SCHEMBL25491161 | 0.89 | SLC1A1 (0.35) | CA12CA14CA2SLC1A1TSHR | |
| SCHEMBL18758702 | 0.88 | CYP2D6 (0.41) | CA2DGAT1CYP2D6LTA4HNOS1 | |
| SCHEMBL1934270 | 0.88 | CYP2D6 (0.41) | CA2DGAT1CYP2D6LTA4HNOS1 | |
| SCHEMBL975517 | 0.88 | CYP2D6 (0.41) | CA2DGAT1CYP2D6LTA4HNOS1 | |
| Hydrochloric Acid SCHEMBL22398615 | 0.86 | CYP2D6 (0.40) | CA2CYP2D6LTA4HNOS1NOS3 | |
| Ammonia Solution, Strong SCHEMBL2393369 | 0.86 | CYP2D6 (0.40) | CA2CYP2D6LTA4HNOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324544-A1 | SUBSTITUTED CYCLIC PYRROLIDINE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324544-A1 | SUBSTITUTED CYCLIC PYRROLIDINE DERIVATIVES | EIF2AK2, NSUN2, RNMT | CA12 4364/4885CA14 4212/4885CA2 4001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.