Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 5/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.52 |
| ▸ | PARP11 | Q9NR21 | 4/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.48 |
| ▸ | CASP6 | P55212 | 2/20 | 0.48 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.48 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL106149 | 0.85 | LRRK2 (0.50) | GSK3BCA12CA9PARP1PARP10 | |
| SCHEMBL29380714 | 0.85 | LRRK2 (0.50) | GSK3BCA12CA9PARP1PARP10 | |
| SCHEMBL4455970 | 0.77 | PARP1 (0.57) | GSK3BCA12CA9PARP1PARP10 | |
| SCHEMBL4567595 | 0.77 | CA12 (0.61) | GSK3BCA12CA9PARP1PARP10 | |
| Phthalimide SCHEMBL14763935 | 0.77 | GSK3B (0.94) | GSK3BCA9PARP1CASP3CASP7 | |
| Phthalimide SCHEMBL27772865 | 0.76 | GSK3B (0.79) | GSK3BCA12CA9PARP1CASP3 | |
| SCHEMBL2127320 | 0.75 | CYP1A2 (0.58) | GSK3BCA12CA9MEN1KMT2A | |
| Phthalimide SCHEMBL14764095 | 0.74 | GSK3B (0.88) | GSK3BPARP1CASP3CASP7CASP6 | |
| Phthalimide SCHEMBL29664386 | 0.74 | GSK3B (0.88) | GSK3BCA12CA9PARP1CASP3 | |
| Phthalimide SCHEMBL28619195 | 0.74 | GSK3B (0.88) | GSK3BCA12CA9PARP1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120062228-A1 | PREPARATION OF POLYAMIDE BLOCK COPOLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| US-8063169-B2 | Preparation of polyamide block copolymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| US-7635747-B2 | Using mixtures or adducts of N-heterocyclic carbenes with metal amides or metal alkoxides as catalysts; the catalysts are stable at polymerization temperatures, and the polymerization is rapid, resulting in high monomer conversion, high molecular weight | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-22 | — | — | US | disclosed |
| US-7514499-B2 | Ring opening polymerization of cyclic amides using N-heterocyclic carbene catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-07 | — | — | US | disclosed |
| US-20070293629-A1 | PREPARATION OF POLAMIDE BLOCK COPOLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-12-20 | — | — | US | disclosed |