⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1299384 | 0.84 | — | — | |
| SCHEMBL4393738 | 0.71 | — | — | |
| SCHEMBL1388602 | 0.69 | — | — | |
| SCHEMBL901692 | 0.65 | — | — | |
| SCHEMBL11394866 | 0.64 | — | — | |
| SCHEMBL11168477 | 0.64 | — | — | |
| SCHEMBL9232755 | 0.64 | — | — | |
| SCHEMBL775329 | 0.62 | — | — | |
| SCHEMBL4304574 | 0.62 | — | — | |
| SCHEMBL3254305 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801057-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TRANS-VINYL SULFIDE ALCOHOLS | SUNTORY LTD (JP) | 2002-01-16 | — | — | EP | claimed |
| US-4500457-A | TREATING AN ACYLOXYAZETIDINONE WITH MERCAPTO COMPOUND, GLYOYLIC ESTER, HALOGENATION AGENT, AND PHOSPHINE COMPOUNT THEN CYCLIZATION | CIBA-GEIGY CORPORATION (US) | 1985-02-19 | — | — | US | claimed |
| US-20090186834-A1 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | MICROBIA, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| WO-2008039829-A2 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2008-04-03 | — | — | WO | disclosed |
| WO-2006102674-A2 | DIPHENYLHETEROCYCLE CHOLESTEROL ABSORPTION INHIBITORS | MICROBIA, INC. (US) | 2006-09-28 | — | — | WO | disclosed |
| EP-0801057-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TRANS-VINYL SULFIDE ALCOHOLS | SUNTORY LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| US-6049009-A | REDUCING A TRANS-VINYLSULFIDE KETONE COMPOUND WITH BORANE REDUCING AGENT IN PRESENCE OF OPTICALLY ACTIVE OXAZABOROLIDINE COMPOUND AND A SULFIDE COMPOUND SELECTED FROM DIMETHYLSULFIDE, METHYLPHENYLSULFIDE, DIPHENYLSULFIDE, DI-N-BUTYLSULFIDE | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0876377-A1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS VIA REDUCTIVE DICARBONYL CYCLIZATION INDUCED BY TRIALKYL PHOSPHITE OF 4-THIOAZETIDINONE DERIVATIVES OBTAINED FROM PENICILLINS | 3 EXO S.r.l. (IT) | 1998-11-11 | — | — | EP | disclosed |
| EP-0801057-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE TRANS-VINYL SULFIDE ALCOHOLS | SUNTORY LIMITED (JP) | 1997-10-15 | — | — | EP | disclosed |
| WO-1997020848-A1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS VIA REDUCTIVE DICARBONYL CYCLIZATION INDUCED BY TRIALKYL PHOSPHITE OF 4-THIOAZETIDINONE DERIVATIVES OBTAINED FROM PENICILLINS | 3 EXO S.R.L. (IT) | 1997-06-12 | — | — | WO | disclosed |
| US-4952690-A | 6-substituted thia-aza compounds | CIBA-GEIGY CORPORATION (US) | 1990-08-28 | — | — | US | disclosed |
| EP-0112283-A1 | Heterocyclyl-thio compounds, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1984-06-27 | — | — | EP | disclosed |
| EP-0110826-A1 | 6-Hydroxy lower alkyl penem compounds, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1984-06-13 | — | — | EP | disclosed |
| EP-0109362-A1 | Hetereocyclic compounds, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1984-05-23 | — | — | EP | disclosed |
| US-4447360-A | Intermediates for thia-aza compounds with a β-lactam ring | CIBA-GEIGY CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0003960-B1 | 6-SUBSTITUTED THIA-AZA-COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1983-06-29 | — | — | EP | disclosed |
| EP-0082113-A1 | 2-Aminobytyl-2-penem derivatives, process for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |
| US-4331676-A | 2-PENEM COMPOUNDS UNSUBSTITUTED IN THE 6 POSITION | CIBA-GEIGY CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |
| EP-0042026-A1 | 3,4-Disubstituted azetidin-2-on compounds and process for their preparation | CIBA-GEIGY AG (CH) | 1981-12-23 | — | — | EP | disclosed |
| EP-0003960-A1 | 6-Substituted thia-aza-compounds, their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1979-09-19 | — | — | EP | disclosed |