Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.41 |
| ▸ | ITGAV | P06756 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 2/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4434047 | 0.93 | KMT2A (0.47) | ITGB3ITGAVGAAKMT2AMEN1 | |
| SCHEMBL4552119 | 0.83 | GAA (0.43) | ITGB3ITGAVGAAKMT2AITGA2B | |
| SCHEMBL4426938 | 0.83 | ITGB3 (0.41) | ITGB3ITGAVGAAKMT2AITGA2B | |
| SCHEMBL4426804 | 0.83 | USP2 (0.40) | ITGB3ITGAVGAAKMT2AMEN1 | |
| SCHEMBL4428522 | 0.81 | ITGB3 (0.40) | ITGB3ITGAVGAAITGA2BTAS1R3 | |
| SCHEMBL4426505 | 0.81 | ITGB3 (0.44) | ITGB3ITGAVGAAKMT2AMEN1 | |
| SCHEMBL4436976 | 0.80 | ITGB3 (0.42) | ITGB3ITGAVGAAKMT2AITGA2B | |
| SCHEMBL4434014 | 0.80 | ITGB3 (0.42) | ITGB3ITGAVGAAKMT2AITGA2B | |
| SCHEMBL4426774 | 0.80 | KMT2A (0.50) | ITGB3ITGAVKMT2AMEN1USP2 | |
| SCHEMBL4428449 | 0.79 | ITGB3 (0.42) | ITGB3ITGAVGAAKMT2AITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213288-B1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2009-01-14 | — | — | EP | disclosed |
| EP-1213288-A1 | Propanoic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-06-12 | — | — | EP | disclosed |