SCHEMBL4428361

SCHEMBL4428361

OCC(O)C[N]CC(O)CO

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.53
ALDH1A1 P00352 1/20 0.53
THRB P10828 1/20 0.42
TDP1 Q9NUW8 2/20 0.33
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
USP2 O75604 1/20 0.30
CYP3A4 P08684 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL27901309 0.76
SCHEMBL2630683 0.73
SCHEMBL8624216 0.73
SCHEMBL10048310 0.73
SCHEMBL1657231 0.72
SCHEMBL22268 0.72
SCHEMBL9333183 0.72
SCHEMBL4557350 0.72
SCHEMBL5519959 0.72
Glycerin SCHEMBL797 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11213852-B2 Photocatalyst layer, photocatalyst, and method for manufacturing photocatalyst SHARP KABUSHIKI KAISHA (JP) 2022-01-04 US disclosed
US-20190329288-A1 PHOTOCATALYST LAYER, PHOTOCATALYST, AND METHOD FOR MANUFACTURING PHOTOCATALYST SHARP KABUSHIKI KAISHA (JP) 2019-10-31 US disclosed
US-7476676-B2 Methods for increasing bone formation using inhibitors of glycogen synthase kinase-3β ROCHE PALO ALTO LLC (US) 2009-01-13 US disclosed
EP-1465610-B1 USE OF A GSK-3BETA INHIBITOR IN THE MANUFACTURE OF A MEDICAMENT FOR INCREASING BONE FORMATION HOFFMANN LA ROCHE (CH) 2008-12-31 EP disclosed
EP-1307447-B1 3-INDOLYL-4-PHENYL-1H-PYRROLE-2,5-DIONE DERIVATIVES AS INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3BETA HOFFMANN LA ROCHE (CH) 2004-12-15 EP disclosed
US-6479490-B2 TREATMENT OF DISEASES CHARACTERIZED BY EXCESS TH2 CYTOKINES AND/ OR AN EXCESS IGE PRODUCTION. SYNTEX (U.S.A.) LLC 2002-11-12 US disclosed
EP-0773936-B1 MACROCYCLIC CHELANTS, THEIR CHELATES AND USES THEREOF IN THE DIAGNOSTIC FIELD BRACCO SPA (IT) 1998-06-17 EP disclosed
US-5708166-A Macrocyclic chelants, their chelates and uses thereof in the diagnostic field DIBRA S.P.A. (IT) 1998-01-13 US disclosed
US-5622688-A CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING DIBRA S.P.A. (IT) 1997-04-22 US disclosed
EP-0325762-B1 Macrocyclic chelating agents and chelates thereof BRACCO SPA (IT) 1995-03-22 EP disclosed
EP-0365541-B1 PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES BRACCO S.p.A. (IT) 1992-08-12 EP disclosed
US-5132409-A Derivatives of 1,4,7,10-Tetraazacyclododecane BRACCO INDUSTRIA CHIMICA S.P.A. (IT) 1992-07-21 US disclosed
US-5066823-A Rearrangement reaction, contrast agent for radiology BRACCO INDUSTRIA CHEMICA S.P.A. (IT) 1991-11-19 US disclosed
EP-0440606-A1 MACROCYCLIC CHELATING AGENTS AND CHELATES THEREOF BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) 1991-08-14 EP disclosed
EP-0365541-A1 PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES. BRACCO IND CHIMICA SPA (IT) 1990-05-02 EP disclosed
EP-0325762-A1 Macrocyclic chelating agents and chelates thereof BRACCO S.p.A. (IT) 1989-08-02 EP disclosed
WO-1989005802-A1 MACROCYCLIC CHELATING AGENTS AND CHELATES THEREOF BRACCO INDUSTRIA CHIMICA S.P.A. (IT) 1989-06-29 WO disclosed
US-4826921-A Coating composition INTERNATIONAL PAINT PUBLIC LIMITED COMPANY (GB) 1989-05-02 US disclosed
WO-1988009328-A1 PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES BRACCO INDUSTRIA CHIMICA S.P.A. (IT) 1988-12-01 WO disclosed
EP-0259172-A2 Coating composition COURTAULDS COATINGS (HOLDINGS) LIMITED (GB) 1988-03-09 EP disclosed