⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428361 | 0.73 | LMNA (0.53) | — | |
| Glycerin SCHEMBL28906248 | 0.72 | — | — | |
| Glycerin SCHEMBL27901309 | 0.71 | — | — | |
| SCHEMBL10605508 | 0.71 | — | — | |
| SCHEMBL7759312 | 0.69 | LMNA (0.58) | — | |
| SCHEMBL3530506 | 0.69 | LMNA (0.58) | — | |
| SCHEMBL2630683 | 0.69 | — | — | |
| Glycerin SCHEMBL757035 | 0.68 | — | — | |
| Glycerin SCHEMBL11026686 | 0.68 | — | — | |
| Glycerin SCHEMBL21820346 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773936-B1 | MACROCYCLIC CHELANTS, THEIR CHELATES AND USES THEREOF IN THE DIAGNOSTIC FIELD | BRACCO SPA (IT) | 1998-06-17 | — | — | EP | disclosed |
| US-5708166-A | Macrocyclic chelants, their chelates and uses thereof in the diagnostic field | DIBRA S.P.A. (IT) | 1998-01-13 | — | — | US | disclosed |
| US-5622688-A | CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING | DIBRA S.P.A. (IT) | 1997-04-22 | — | — | US | disclosed |
| WO-1996004259-A1 | MACROCYCLIC CHELANTS, THEIR CHELATES AND USES THEREOF IN THE DIAGNOSTIC FIELD | BRACCO S.P.A. (IT) | 1996-02-15 | — | — | WO | disclosed |
| EP-0325762-B1 | Macrocyclic chelating agents and chelates thereof | BRACCO SPA (IT) | 1995-03-22 | — | — | EP | disclosed |
| EP-0365541-B1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES | BRACCO S.p.A. (IT) | 1992-08-12 | — | — | EP | disclosed |
| US-5132409-A | Derivatives of 1,4,7,10-Tetraazacyclododecane | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1992-07-21 | — | — | US | disclosed |
| US-5066823-A | Rearrangement reaction, contrast agent for radiology | BRACCO INDUSTRIA CHEMICA S.P.A. (IT) | 1991-11-19 | — | — | US | disclosed |
| EP-0440606-A1 | MACROCYCLIC CHELATING AGENTS AND CHELATES THEREOF | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1991-08-14 | — | — | EP | disclosed |
| EP-0365541-A1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES. | BRACCO IND CHIMICA SPA (IT) | 1990-05-02 | — | — | EP | disclosed |
| EP-0325762-A1 | Macrocyclic chelating agents and chelates thereof | BRACCO S.p.A. (IT) | 1989-08-02 | — | — | EP | disclosed |
| WO-1989005802-A1 | MACROCYCLIC CHELATING AGENTS AND CHELATES THEREOF | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1989-06-29 | — | — | WO | disclosed |
| WO-1988009328-A1 | PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1988-12-01 | — | — | WO | disclosed |
| US-3998827-A | HYPOTENSIVE AGENTS | THE UPJOHN COMPANY (US) | 1976-12-21 | — | — | US | disclosed |