Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | GLP1R | P43220 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4041010 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPK1HSD17B10KDM4EL3MBTL1 | |
| SCHEMBL29739916 | 0.77 | GLP1R (0.49) | ALDH1A1MAPK1HSD17B10L3MBTL1GLP1R | |
| SCHEMBL4019772 | 0.77 | GLP1R (0.49) | ALDH1A1MAPK1HSD17B10L3MBTL1GLP1R | |
| SCHEMBL25771606 | 0.75 | TSHR (0.47) | ALDH1A1MAPK1HSD17B10KDM4EL3MBTL1 | |
| SCHEMBL23618033 | 0.75 | NR1H2 (0.47) | ALDH1A1MAPK1HSD17B10KDM4EL3MBTL1 | |
| SCHEMBL5886537 | 0.73 | MAPT (0.43) | ALDH1A1MAPK1HSD17B10KDM4EL3MBTL1 | |
| SCHEMBL5888721 | 0.72 | KDM4E (0.39) | ALDH1A1MAPK1HSD17B10KDM4EL3MBTL1 | |
| SCHEMBL5886482 | 0.71 | KDM4E (0.42) | ALDH1A1MAPK1HSD17B10KDM4EL3MBTL1 | |
| SCHEMBL7634356 | 0.70 | ESR1 (0.50) | ALDH1A1MAPK1HSD17B10KDM4EL3MBTL1 | |
| SCHEMBL31208503 | 0.70 | MAPT (0.40) | ALDH1A1MAPK1HSD17B10L3MBTL1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069334-A1 | Pyridazine based alpha-helix mimetics | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069334-A1 | Pyridazine based alpha-helix mimetics | H1-4, H1-5, H1-0 | ALDH1A1 3022/4885MAPK1 2985/4885HSD17B10 2354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.