Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.41 |
| ▸ | VHL | P40337 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRN | P28799 | 2/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428531 | 1.00 | ATM (0.53) | ATMALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL4434719 | 0.86 | ATM (0.55) | ATMVHL | |
| SCHEMBL4434711 | 0.86 | ATM (0.55) | ATMVHL | |
| SCHEMBL4432443 | 0.85 | ATM (0.54) | ATMVHL | |
| SCHEMBL4432439 | 0.85 | ATM (0.54) | ATMVHL | |
| SCHEMBL26079416 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1LMNAFOLH1 | |
| SCHEMBL4439283 | 0.85 | ATM (0.54) | ATMFOLH1VHLMAPT | |
| SCHEMBL4439286 | 0.85 | ATM (0.54) | ATMFOLH1VHLMAPT | |
| SCHEMBL4437826 | 0.84 | ATM (0.53) | ATMFOLH1VHLPOLB | |
| SCHEMBL4437822 | 0.84 | ATM (0.53) | ATMFOLH1VHLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2117536-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | Beiersdorf AG (DE) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008101693-A2 | COSMETIC AND PHARMACEUTICAL APPLICATIONS OF N-ACYLATED AMINO ACIDS AND STRUCTURALLY RELATED COMPOUNDS | BEIERSDORF AG (DE) | 2008-08-28 | — | — | WO | disclosed |