Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 4/20 | 0.36 |
| ▸ | RXRB | P28702 | 3/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.32 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.32 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.32 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.32 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4428610 | 0.94 | RXRA (0.39) | PPARGRXRARXRBHNF4ASMN1; SMN2 | |
| SCHEMBL4428575 | 0.87 | SLC1A3 (0.40) | RXRARXRBHNF4AHPGDADRB2 | |
| SCHEMBL4428613 | 0.84 | RXRA (0.36) | PPARGEPHX2RXRARXRBHNF4A | |
| SCHEMBL480503 | 0.82 | EPHX2 (0.49) | PPARGPPARAEPHX2SMN1; SMN2HPGD | |
| SCHEMBL4421789 | 0.81 | SLC6A4 (0.37) | TSHRSLC6A2SLC6A3 | |
| SCHEMBL4422002 | 0.80 | SLC6A4 (0.35) | SLC6A2SLC6A3 | |
| SCHEMBL4424402 | 0.79 | SLC6A4 (0.36) | RXRAHNF4ATSHRSLC6A2SLC6A3 | |
| SCHEMBL4414842 | 0.79 | BCHE (0.36) | RXRAHNF4ATSHR | |
| SCHEMBL4427246 | 0.78 | GAA (0.38) | RXRAHNF4ATSHRSLC6A2SLC6A3 | |
| SCHEMBL4422392 | 0.78 | ELANE (0.33) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620475-B1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | BASF SE (DE) | 2009-11-11 | — | — | EP | disclosed |
| US-7462650-B2 | Trifunctional photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-12-09 | — | — | US | disclosed |
| US-20060270748-A1 | Novel trifunctional photoinitiators | IGM GROUP B.V. (NL) | 2006-11-30 | — | — | US | disclosed |
| EP-1620475-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099262-A1 | NOVEL TRIFUNCTIONAL PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-11-18 | — | — | WO | disclosed |