Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 11/20 | 0.60 |
| ▸ | AR | P10275 | 4/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3395694 | 0.90 | VDR (0.64) | VDRARHDAC6HDAC3HDAC1 | |
| SCHEMBL6437088 | 0.80 | HDAC6 (0.53) | VDRARHDAC6HDAC3HDAC1 | |
| SCHEMBL16183084 | 0.77 | VDR (0.77) | VDRARHDAC6HDAC3HDAC1 | |
| SCHEMBL13366805 | 0.74 | HDAC6 (0.66) | VDRARHDAC6HDAC3HDAC1 | |
| SCHEMBL20059951 | 0.74 | VDR (0.60) | VDRARHDAC6HDAC3HDAC1 | |
| SCHEMBL15076968 | 0.73 | VDR (0.75) | VDRARHDAC6HDAC3HDAC1 | |
| SCHEMBL2949160 | 0.73 | VDR (0.75) | VDRARHDAC6HDAC3HDAC1 | |
| SCHEMBL16178018 | 0.73 | VDR (0.75) | VDRARHDAC6HDAC3HDAC1 | |
| Lg-190178 SCHEMBL29754199 | 0.72 | VDR (1.00) | VDRAR | |
| SCHEMBL2946827 | 0.72 | VDR (0.73) | VDRARHDAC6HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511740-B1 | PHENYL-THIOPHENE TYPE VITAMIN D RECEPTOR MODULATORS | LILLY CO ELI (US) | 2009-07-08 | — | — | EP | disclosed |