Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 11/20 | 0.53 |
| ▸ | LHCGR | P22888 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | FSHR | P23945 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 3/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.45 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429274 | 0.90 | LHCGR (0.66) | BRAFLHCGRTSHRFSHR | |
| SCHEMBL5030719 | 0.88 | BRAF (0.51) | BRAFLHCGRTSHRFSHR | |
| SCHEMBL5569916 | 0.87 | BRAF (0.51) | BRAFLHCGRTSHRFSHRPDE4A | |
| SCHEMBL4425219 | 0.87 | BRAF (0.55) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4421622 | 0.83 | LHCGR (0.60) | BRAFLHCGRTSHRFSHRPDE4A | |
| SCHEMBL5030680 | 0.82 | LHCGR (0.53) | BRAFLHCGRTSHRFSHRPDE4A | |
| SCHEMBL5026102 | 0.82 | LHCGR (0.53) | BRAFLHCGRTSHRFSHRPDE4A | |
| SCHEMBL5024538 | 0.81 | LHCGR (0.52) | BRAFLHCGRTSHRFSHRPDE4A | |
| SCHEMBL5024555 | 0.81 | LHCGR (0.55) | BRAFLHCGRTSHRFSHRPDE4A | |
| SCHEMBL6217358 | 0.81 | LHCGR (0.57) | BRAFLHCGRTSHRFSHRPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1247594-C | Bicyclic heteroaromatic compounds | OKZO NOBEL N V (NL) | 2006-03-29 | — | — | CN | claimed |
| CN-1462273-A | Bicyclic heteroaromatic compounds | OKZO NOBEL N V (NL) | 2003-12-17 | — | — | CN | claimed |
| US-7618963-B2 | Bicyclic heteroaromatic compounds | N.V. ORGANON (NL) | 2009-11-17 | — | — | US | disclosed |
| EP-1886999-A2 | Bicyclic heteroaromatic compound | N.V. Organon (NL) | 2008-02-13 | — | — | EP | disclosed |
| EP-1322651-B1 | BICYCLIC HETEROAROMATIC COMPOUNDS | ORGANON NV (NL) | 2008-01-23 | — | — | EP | disclosed |
| US-20070197527-A1 | Bicyclic heteroaromatic compounds | N.V. ORGANON (NL) | 2007-08-23 | — | — | US | disclosed |
| CN-1247594-C | Bicyclic heteroaromatic compounds | OKZO NOBEL N V (NL) | 2006-03-29 | — | — | CN | disclosed |
| CN-1462273-A | Bicyclic heteroaromatic compounds | OKZO NOBEL N V (NL) | 2003-12-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197527-A1 | Bicyclic heteroaromatic compounds | NR5A1, CYP19A1, FSHR | BRAF 4242/4885LHCGR 10/4885TSHR 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.