Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26326653 | 0.76 | CYP2D6 (0.46) | CHRM2CHRM1KCNH2CYP2D6L3MBTL1 | |
| SCHEMBL27997622 | 0.76 | CHRM3 (0.47) | CHRM2CHRM1KCNH2CYP2D6SLC18A3 | |
| SCHEMBL933428 | 0.76 | CHRM3 (0.45) | CHRM2CHRM1KCNH2CYP2D6L3MBTL1 | |
| SCHEMBL2791594 | 0.74 | L3MBTL1 (0.48) | CHRM2CHRM1KCNH2CYP2D6L3MBTL1 | |
| SCHEMBL4278250 | 0.68 | L3MBTL1 (0.45) | L3MBTL1CHRM3NPC1RAB9ATSHR | |
| SCHEMBL4288037 | 0.67 | L3MBTL1 (0.44) | L3MBTL1NPC1RAB9ATSHRTAAR1 | |
| SCHEMBL26986096 | 0.67 | SLC18A3 (0.38) | CHRM2CHRM1KCNH2CYP2D6L3MBTL1 | |
| Tridihexethyl SCHEMBL94230 | 0.67 | CHRM2 (1.00) | CHRM2CHRM1KCNH2CYP2D6SLC6A3 | |
| Tridihexethyl SCHEMBL2296006 | 0.67 | CHRM2 (1.00) | CHRM2CHRM1KCNH2CYP2D6SLC6A3 | |
| SCHEMBL25971519 | 0.66 | SLC6A2 (0.44) | CHRM2CHRM1KCNH2CYP2D6SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026807-A1 | USE OF PARASYMPATHOLYTIC SUBSTANCES TO ENHANCE AND ACCELERATE STEM CELL DIFFERENTIATION, RELATED METHOD AND COMPOSITIONS | Universita' Degli Studi di Torino (IT) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007135574-A1 | USE OF PARASYMPATHOLYTIC SUBSTANCES TO ENHANCE AND ACCELERATE STEM CELL DIFFERENTIATION, RELATED METHOD AND COMPOSITIONS | UNIVERSITA' DEGLI STUDI DI TORINO (IT) | 2007-11-29 | — | — | WO | disclosed |