SCHEMBL4429554

SCHEMBL4429554

CCCCCCCCCCCCCCCCCCCCCCOc1cc(OCCCCCCCCCCCCCCCCCCCCCC)c(N)cc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
MCHR1 Q99705 2/20 0.44
TLR8 Q9NR97 2/20 0.44
TSHR P16473 1/20 0.44
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.42
USP2 O75604 1/20 0.42
TP53 P04637 1/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
CASP1 P29466 1/20 0.42
HTT P42858 1/20 0.42
CASP7 P55210 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27224315 0.89 ESR1 (0.44) ESR1CYP1A2CYP2C9CYP2C19MCHR1
SCHEMBL1553685 0.89 CYP1A2 (0.50) CYP1A2CYP2C9CYP2C19MCHR1TLR8
SCHEMBL1553131 0.89 CYP1A2 (0.50) CYP1A2CYP2C9CYP2C19MCHR1TLR8
SCHEMBL1554055 0.89 CYP1A2 (0.50) CYP1A2CYP2C9CYP2C19MCHR1TLR8
SCHEMBL1553655 0.89 CYP1A2 (0.50) CYP1A2CYP2C9CYP2C19MCHR1TLR8
SCHEMBL1553128 0.89 CYP1A2 (0.50) CYP1A2CYP2C9CYP2C19MCHR1TLR8
SCHEMBL1554235 0.89 CYP1A2 (0.50) CYP1A2CYP2C9CYP2C19MCHR1TLR8
SCHEMBL11579460 0.87 CYP1A2 (0.52) CYP1A2CYP2C9CYP2C19MCHR1TLR8
SCHEMBL862599 0.85 ESR1 (0.51) ESR1MCHR1TLR8TSHRALDH1A1
SCHEMBL13475563 0.85 ESR1 (0.51) ESR1MCHR1TLR8TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2003104-B1 REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT JITSUBO CO LTD (JP) 2015-07-01 EP disclosed
EP-2003104-A9 REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT National University Corporation Tokyo University of Agriculture and Technology (JP) 2009-04-15 EP disclosed
EP-2003104-A2 REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT National University Corporation Tokyo University of Agriculture and Technology (JP) 2008-12-17 EP disclosed