Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4436860 | 0.84 | NPC1 (0.42) | ALDH1A1LMNASMN1; SMN2MAPTNPC1 | |
| SCHEMBL4608551 | 0.82 | APP (0.46) | ALDH1A1CYP3A4SMN1; SMN2HTR7MAPT | |
| SCHEMBL4426238 | 0.80 | PDE2A (0.40) | MAPTL3MBTL1RAB9ANPSR1 | |
| SCHEMBL4429990 | 0.79 | ELANE (0.38) | ACHEALDH1A1CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL4433438 | 0.76 | MAOB (0.37) | ALDH1A1SMN1; SMN2L3MBTL1NPC1RAB9A | |
| SCHEMBL4431124 | 0.76 | ELANE (0.36) | ALDH1A1SMN1; SMN2MAPTHPGDNPC1 | |
| SCHEMBL22115865 | 0.75 | — | — | |
| SCHEMBL3958057 | 0.75 | ACHE (0.52) | ACHEALDH1A1CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL14003494 | 0.72 | KMT2A (0.51) | ACHEALDH1A1CYP3A4LMNASMN1; SMN2 | |
| SCHEMBL29363658 | 0.72 | KMT2A (0.51) | ACHEALDH1A1CYP3A4LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121660-A2 | FUNGICIDAL AMIDES | E. I. Du Pont de Nemours and Company (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |
| WO-2008091580-A2 | FUNGICIDAL AMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |