Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL473080 | 0.96 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1MEN1LMNA | |
| SCHEMBL7638 | 0.96 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1MEN1LMNA | |
| SCHEMBL29405187 | 0.96 | ALDH1A1 (0.63) | ALDH1A1TSHRTDP1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL2848046 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1LMNA | |
| SCHEMBL15162654 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1LMNA | |
| Lithium SCHEMBL10426887 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1LMNA | |
| SCHEMBL8719955 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL10895543 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1LMNA | |
| SCHEMBL22496001 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1LMNA | |
| SCHEMBL8045918 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRTDP1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391482-B1 | Polypropylene composition | BOREALIS TECH OY (FI) | 2009-05-20 | — | — | EP | disclosed |
| EP-1294782-B1 | USE OF MODIFIED OLEFIN POLYMERS FOR PRODUCING POLYOLEFIN PRODUCTS WITH IMPROVED TOUGHNESS, STRENGTH AND HEAT RESISTANCE | BOREALIS POLYOLEFINE GMBH (AT) | 2007-01-10 | — | — | EP | disclosed |
| US-6797778-B2 | Use of modified olefin polymers for producing polyolefin products with improved toughness, strength and heat resistance | BOREALIS GMBH (AU) | 2004-09-28 | — | — | US | disclosed |
| EP-1391482-A1 | Polypropylene composition | Borealis GmbH (AT) | 2004-02-25 | — | — | EP | disclosed |
| US-20030176590-A1 | Use of modified olefin polymers for producing polyolefin products with improved toughness, strength and heat resistance | BOREALIS GMBH (AT) | 2003-09-18 | — | — | US | disclosed |
| EP-1294782-A1 | USE OF MODIFIED OLEFIN POLYMERS FOR PRODUCING POLYOLEFIN PRODUCTS WITH IMPROVED TOUGHNESS, STRENGTH AND HEAT RESISTANCE | Borealis GmbH (AT) | 2003-03-26 | — | — | EP | disclosed |
| US-6537473-B2 | Process of making polyolefin fibers | BOREALIS GMBH (AT) | 2003-03-25 | — | — | US | disclosed |
| US-20020002241-A1 | Polyolefin fibers and polyolefin yarns and textile fabrics produced therefrom | BOREALIS GMBH | 2002-01-03 | — | — | US | disclosed |
| EP-1167404-A1 | Polyolefin products with improved toughness, strength and heat resistance | Borealis GmbH (AT) | 2002-01-02 | — | — | EP | disclosed |
| WO-2001098385-A1 | USE OF MODIFIED OLEFIN POLYMERS FOR PRODUCING POLYOLEFIN PRODUCTS WITH IMPROVED TOUGHNESS, STRENGTH AND HEAT RESISTANCE | BOREALIS GMBH (AT) | 2001-12-27 | — | — | WO | disclosed |
| US-6218011-B1 | Polyolefin fibers and polyolefin yarns and textile fabrics produced therefrom | BOREALIS GMBH (AT) | 2001-04-17 | — | — | US | disclosed |