SCHEMBL4430

SCHEMBL4430

O=C1C(O)=C(O)O[C@@H]1[C@@H](O)CO

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.56
MAPT P10636 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
MANBA O00462 1/20 0.39
THRB P10828 1/20 0.39
HIF1A Q16665 1/20 0.39
TYR P14679 2/20 0.35
HSPD1 P10809 1/20 0.30
HSPE1 P61604 1/20 0.30
TST Q16762 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL332736 1.00 LMNA (0.56) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL3700961 1.00 LMNA (0.56) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL3700963 1.00 LMNA (0.56) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL28295650 0.90 LMNA (0.47) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL29881878 0.82 LMNA (0.55) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL30968979 0.81 LMNA (0.49) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL1532401 0.81 MAPT (0.37) LMNAMAPTL3MBTL1
SCHEMBL16997433 0.79 MAPT (0.36) LMNAMAPTL3MBTL1
Water SCHEMBL66327 0.78 LMNA (0.50) LMNAMAPTL3MBTL1MANBATHRB
SCHEMBL9882794 0.78 MAPT (0.36) LMNAMAPTL3MBTL1HSPD1HSPE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 174238 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144845-A1 PHARMACEUTICAL COMPOSITION COMPRISING ECHINOCANDIN ANALOG AND PREPARATION METHOD FOR PHARMACEUTICAL COMPOSITION JIANGSU HENGRUI PHARMACEUTICALS CO., LTD. (CN) 2026-05-28 US claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4746875-A2 CARCINOGENESIS REDUCTION WITH PENTAAZA MACROCYCLIC RING COMPLEX Galera Labs, LLC (US) 2026-05-27 EP claimed
CN-122080105-A Estrol antidepressant derivative, preparation method and medical application thereof 2026-05-26 CN claimed
US-12637610-B2 Low concentration synthetic polymer fracturing fluid with ascorbic acid CNPC USA CORPORATION (US) 2026-05-26 US claimed
CN-117865962-B Indole diketone and indole quinoxaline derivative fluorescent compound, preparation method and application thereof JIANGNAN UNIVERSITY (CN) 2026-05-26 CN claimed
CN-120754262-B Nucleic acid delivery vector and preparation method and application thereof Shenzhen Jinlin Biotechnology Co.,Ltd. (CN) 2026-05-26 CN claimed
US-12642028-B2 Methods for wet atomic layer etching of tungsten TOKYO ELECTRON LIMITED (JP) 2026-05-26 US claimed
US-20260137817-A1 COMBINATION CANCER IMMUNOTHERAPY WITH PENTAAZA MACROCYCLIC RING COMPLEX GALERA LABS LLC (US) 2026-05-21 US claimed
US-12629358-B2 Compound used as RET kinase inhibitor and application thereof TYK MEDICINES, INC. (CN) 2026-05-19 US claimed
US-4107433-A Phthalidyl ester of 3-carbomoyloxy cephalosporin derivatives BEECHAM GROUP LIMITED (GB) 1978-08-15 US claimed
US-4097428-A ANTIBIOTIC FROM FERNENTATION OF MICROMONOSPORA ABBOTT LABORATORIES (US) 1978-06-27 US claimed
US-4089957-A ACID SALT OF MOROXYDINE AB KABI (SW) 1978-05-16 US claimed
US-4075314-A SKELETAL IMAGING MALLINCKRODT, INC. (US) 1978-02-21 US claimed
US-4057620-A CRATAGEUS EXTRACT, A VITAMIN, QUININE SALT LABORATOIRE THERANOL (FR) 1977-11-08 US claimed
US-4032406-A MEASURING OXYGEN-UPTAKE VIA HYDROXYLATION OF DOPAMINE OR TYRAMINE; ASCORBATE, FUMARATE MONSANTO COMPANY (US) 1977-06-28 US claimed
US-4027009-A QUATERNARY POLY(ALKYLIMINO)ALKYLENE AS BILE ACID BINDERS MERCK & CO., INC. (US) 1977-05-31 US claimed
US-3966745-A TREATMENT OF VASCULAR DISORDERS SYNTHELABO (FR) 1976-06-29 US claimed
US-3966974-A LESS PRODUCTION OF NITROSAMINES CANADA PACKERS LIMITED (CA) 1976-06-29 US claimed
US-3931400-A CULTIVATION OF MICROMONOSPORA, ANTIBIOTIC ABBOTT LABORATORIES (US) 1976-01-06 US claimed