Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1019958 | 0.93 | MEN1 (0.67) | MEN1KMT2AATMMAPTSMN1; SMN2 | |
| SCHEMBL12240580 | 0.77 | SIRT6 (0.74) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8931734 | 0.77 | MEN1 (0.62) | MEN1KMT2AATMMAPTSMN1; SMN2 | |
| SCHEMBL1126953 | 0.75 | MEN1 (0.64) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL8931637 | 0.74 | MEN1 (0.70) | MEN1KMT2AATMMAPTSMN1; SMN2 | |
| SCHEMBL22495422 | 0.74 | MEN1 (0.62) | MEN1KMT2AATMMAPTSMN1; SMN2 | |
| SCHEMBL22495404 | 0.74 | MEN1 (0.62) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL22465858 | 0.74 | KMT2A (1.00) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL1126486 | 0.74 | SIRT6 (0.56) | MEN1KMT2AATMMAPTSMN1; SMN2 | |
| SCHEMBL3440078 | 0.73 | MEN1 (0.77) | MEN1KMT2AATMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097413-A1 | 2-[(2-SUBSTITUTED)-IND0LIZIN-3-YL]-2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G Limited (GB) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008062182-A1 | 2- [ (2-SUBSTITUTED) -IND0LIZIN-3-YL] -2-OXO-ACETAMIDE DERIVATIVES AS ANTIFUNGAL AGENTS | F2G LTD (GB) | 2008-05-29 | — | — | WO | disclosed |