SCHEMBL4430289

SCHEMBL4430289

O=C(O)c1cccc(-c2cccc3c2Cc2ccccc2-3)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 2/20 0.58
KMO O15229 1/20 0.53
FOLH1 Q04609 3/20 0.51
SRD5A1 P18405 1/20 0.50
PTGER1 P34995 1/20 0.46
TDP2 O95551 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
NR1H4 Q96RI1 1/20 0.45
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
DDT P30046 1/20 0.43
HSP90AA1 P07900 1/20 0.43
HTR7 P34969 1/20 0.43
HTR2B P41595 1/20 0.43
FNTA P49354 1/20 0.42
FNTB P49356 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27996741 0.89 SRD5A2 (0.55) SRD5A2KMOFOLH1SRD5A1TDP2
SCHEMBL27719863 0.87 NPC1 (0.51) SRD5A2TDP2NPC1RAB9AHTR7
SCHEMBL28489611 0.86 SRD5A2 (0.56) SRD5A2FOLH1SRD5A1NPC1RAB9A
SCHEMBL21439807 0.84 SRD5A2 (0.57) SRD5A2FOLH1SRD5A1NPC1RAB9A
SCHEMBL28851607 0.82 PNMT (0.52) SRD5A2NPC1RAB9AHTR7HTR2B
SCHEMBL22721243 0.82 AKR1C3 (0.58) SRD5A2KMOSRD5A1NPC1RAB9A
SCHEMBL5798409 0.81 HSP90AA1 (0.49) SRD5A2SRD5A1NPC1RAB9AHSP90AA1
SCHEMBL70992 0.80 PNMT (0.53) NPC1RAB9AHTR7HTR2B
SCHEMBL29809707 0.80 PNMT (0.53) NPC1RAB9AHTR7HTR2B
SCHEMBL29401802 0.80 PNMT (0.53) NPC1RAB9AHTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107429033-B Resin composition and optical lens 大阪燃气化学有限公司 2020-11-24 CN disclosed
CN-101268119-B Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE CO 2011-08-17 CN disclosed
US-7608928-B2 Laminated body and semiconductor device JSR CORPORATION (JP) 2009-10-27 US disclosed
CN-101268119-A Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE CO (JP) 2008-09-17 CN disclosed