Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.79 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL442778 | 0.98 | MAPT (0.77) | MAPTRAB9ATDP1L3MBTL1CA1 | |
| SCHEMBL8683825 | 0.91 | MAPT (0.77) | MAPTRAB9ATDP1L3MBTL1CA1 | |
| SCHEMBL13252834 | 0.90 | MAPT (0.75) | MAPTRAB9ATDP1L3MBTL1CA1 | |
| Hydrochloric Acid SCHEMBL6982145 | 0.90 | MAPT (0.74) | MAPTRAB9ATDP1L3MBTL1CA1 | |
| SCHEMBL1951546 | 0.89 | MAPT (1.00) | MAPTRAB9ATDP1L3MBTL1CA1 | |
| SCHEMBL4204731 | 0.88 | MAPT (0.72) | MAPTRAB9ATDP1L3MBTL1CA1 | |
| Hydrochloric Acid SCHEMBL444912 | 0.88 | MAPT (0.72) | MAPTRAB9ATDP1L3MBTL1CA1 | |
| SCHEMBL8708489 | 0.88 | MAPT (0.72) | MAPTRAB9ATDP1L3MBTL1CA1 | |
| SCHEMBL6552089 | 0.88 | MAPT (0.72) | MAPTRAB9ATDP1L3MBTL1CA1 | |
| SCHEMBL20692508 | 0.88 | MAPT (0.66) | MAPTRAB9ATDP1L3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527237-A | Method for preparing abemostat, intermediate and preparation method of intermediate | 上海工程技术大学 | 2021-10-22 | — | — | CN | claimed |
| JP-63112543-A | — | — | None | — | — | JP | disclosed |
| JP-63112542-A | — | — | None | — | — | JP | disclosed |
| CN-118420529-A | Novel estrogen receptor down-regulator compound, preparation method and application | 南京中医药大学 | 2024-08-02 | — | — | CN | disclosed |
| CN-109734690-B | Novel abexinostat salts, related crystalline forms, process for their preparation and pharmaceutical compositions containing them | 制药公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-113527237-A | Method for preparing abemostat, intermediate and preparation method of intermediate | 上海工程技术大学 | 2021-10-22 | — | — | CN | disclosed |
| CN-113527237-A | Method for preparing abemostat, intermediate and preparation method of intermediate | 上海工程技术大学 | 2021-10-22 | — | — | CN | disclosed |
| WO-2021062482-A1 | ANTIVIRAL COMPOUNDS AND THEIR USE | Salut Products Pty Ltd (AU) | 2021-04-08 | — | — | WO | disclosed |
| US-10898461-B2 | Salts of 3-[(dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoyl) phenoxy]ethyli-1-benzofuran-2-carboxamide, related crystalline forms, method for preparing the same and pharmaceutical compositions containing the same | PHARMACYCLICS LLC (US) | 2021-01-26 | — | — | US | disclosed |
| EP-3189040-B1 | NOVEL SALTS OF 3-[(DIMETHYLAMINO)METHYL]-N-{2-[4-(HYDROXYCARBAMOYL) PHENOXY]ETHYL}-1-BENZOFURAN-2-CARBOXAMIDE, RELATED CRYSTALLINE FORMS, METHOD FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PHARMACYCLICS LLC (US) | 2020-07-29 | — | — | EP | disclosed |
| WO-1996035671-A1 | β-ADRENERGIC AGONISTS | PFIZER INC. (US) | 1996-11-14 | — | — | WO | disclosed |
| WO-1996035670-A1 | β-ADRENERGIC AGONISTS | PFIZER INC. (US) | 1996-11-14 | — | — | WO | disclosed |
| WO-1995032710-A1 | COMPOUNDS FOR INHIBITING OSTEOCLAST-MEDIATED BONE RESORPTION | MERCK & CO., INC. (US) | 1995-12-07 | — | — | WO | disclosed |
| EP-0147211-B1 | 4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR THEIR PREPARATION | SYNTEX (U.S.A.) INC. (US) | 1990-09-12 | — | — | EP | disclosed |
| US-4831055-A | ANTILIPEMIC AND ANTICHOLESTEROL AGENTS | NIPPON SHINYAKU CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| JP-S63112542-A | PRODUCTION OF ALKOXYCARBONYL-SUBSTITUTED PHENOXYETHYLAMINES | NIPPON SHOKUBAI KAGAKU KOGYO CO LTD | 1988-05-17 | — | — | JP | disclosed |
| JP-S63112543-A | PRODUCTION OF ALKOXYCARBONYL-SUBSTITUTED PHENOXYETHYLAMINES | NIPPON SHOKUBAI KAGAKU KOGYO CO LTD | 1988-05-17 | — | — | JP | disclosed |
| US-4657893-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-04-14 | — | — | US | disclosed |
| EP-0147211-A2 | 4H-3,1-benzoxazin-4-ones and related compounds, pharmaceutical compositions containing them, and processes for their preparation | SYNTEX (U.S.A.) INC. (US) | 1985-07-03 | — | — | EP | disclosed |
| US-3940407-A | β-Adrenergic blocking agents in the 1,2,3-thiadiazole series | SYNTEX (U.S.A.) INC. (US) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10898461-B2 | Salts of 3-[(dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoyl) phenoxy]ethyli-1-benzofuran-2-carboxamide, related crystalline forms, method for preparing the same and pharmaceutical compositions containing the same | CA13, CA1, CPS1 | MAPT 1355/4885RAB9A 3793/4885TDP1 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.