Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552089 | 1.00 | MAPT (0.72) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL4204731 | 1.00 | MAPT (0.72) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL444912 | 0.97 | MAPT (0.72) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL8683825 | 0.93 | MAPT (0.77) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL6982145 | 0.92 | MAPT (0.74) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL5054312 | 0.92 | MAPT (0.85) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL20692508 | 0.89 | MAPT (0.66) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL19729163 | 0.89 | MAPT (0.70) | MAPTRAB9AL3MBTL1TDP1CA1 | |
| SCHEMBL443043 | 0.88 | MAPT (0.79) | MAPTRAB9AGAAL3MBTL1TDP1 | |
| SCHEMBL6132720 | 0.87 | MAPT (0.77) | MAPTRAB9AGAAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998054142-A1 | CYANOGUANIDINES AS CELL PROLIFERATION INHIBITORS | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1998-12-03 | — | — | WO | disclosed |