Succinic Acid Diethyl Ester

Succinic Acid Diethyl Ester

SCHEMBL4430582

CCOC(=O)CCC(=O)OCC.OCCO

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.57
MGAM O43451 1/20 0.57
SI P14410 1/20 0.57
MGAM2 Q2M2H8 1/20 0.57
CYP1A2 P05177 1/20 0.56
CYP4F2 P78329 3/20 0.55
CYP4A11 Q02928 3/20 0.55
ALDH1A1 P00352 4/20 0.52
TRPA1 O75762 1/20 0.52
LMNA P02545 2/20 0.47
POLB P06746 2/20 0.47
TSHR P16473 1/20 0.47
HSD17B10 Q99714 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.44
NR1I2 O75469 1/20 0.44
PGR P06401 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
PTGS2 P35354 1/20 0.44
PDE4D Q08499 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid Diethyl Ester SCHEMBL28083672 0.92 GAA (0.60) GAAMGAMSIMGAM2CYP1A2
Succinic Acid Diethyl Ester SCHEMBL27768067 0.91 GAA (0.67) GAAMGAMSIMGAM2CYP1A2
Succinic Acid Diethyl Ester SCHEMBL22780 0.91 GAA (0.67) GAAMGAMSIMGAM2CYP1A2
Ethylene Glycol SCHEMBL11418369 0.91 CYP4F2 (0.48) GAAMGAMSIMGAM2CYP1A2
Ethylene Glycol SCHEMBL3030844 0.91 CYP4F2 (0.48) GAAMGAMSIMGAM2CYP1A2
Ethylene Glycol SCHEMBL19921004 0.91 CYP4F2 (0.48) GAAMGAMSIMGAM2CYP1A2
Ethylene Glycol SCHEMBL11008721 0.90 CYP1A2 (0.64) GAAMGAMSIMGAM2CYP1A2
Ethylene Glycol SCHEMBL10727727 0.90 ALDH1A1 (0.52) GAAMGAMSIMGAM2CYP1A2
SCHEMBL6403 0.89
SCHEMBL30800905 0.89 GAA (0.65) GAAMGAMSIMGAM2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1455366-B1 PROTON CONDUCTOR, SINGLE-ION CONDUCTOR, AND PROCESSES FOR PRODUCING THESE SONY CORP (JP) 2009-09-02 EP disclosed
US-7179559-B2 Proton conductor, single-ion conductor, and processes for producing these SONY CORPORATION (JP) 2007-02-20 US disclosed
EP-1455366-A1 PROTON CONDUCTOR, SINGLE-ION CONDUCTOR, AND PROCESSES FOR PRODUCING THESE Sony Corporation (JP) 2004-09-08 EP disclosed
US-20040062972-A1 Proton conductor, single-ion conductor, and processes for producing these SONY COPORATION (JP) 2004-04-01 US disclosed
EP-1178101-A2 Low pollution fuel Hamada, Yoshiro (JP) 2002-02-06 EP disclosed