SCHEMBL443059

SCHEMBL443059

NP(=O)(O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.62
CA4 P22748 1/20 0.62
CA5A P35218 1/20 0.62
CFTR P13569 1/20 0.54
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
ALDH1A1 P00352 3/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
GAA P10253 2/20 0.44
USP2 O75604 1/20 0.44
ESR1 P03372 1/20 0.44
SRC P12931 2/20 0.42
MAPT P10636 2/20 0.42
HSD17B10 Q99714 1/20 0.42
PTPN1 P18031 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALPG P10696 1/20 0.41
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL10908266 0.97 CA2 (0.59) CA2CA4CA5ACFTRALOX15
SCHEMBL7466860 0.83 CA2 (0.62) CA2CA4CA5ACFTRALOX15
Phenylphosphonic Acid SCHEMBL269853 0.77 CA2 (1.00) CA2CA4CA5ACFTRALOX15
SCHEMBL191567 0.77 CA2 (0.68) CA2CA4CA5ACFTRALOX15
SCHEMBL1382564 0.77 CA2 (0.52) CA2CA4CA5ACFTRALOX15
Phenylphosphonic Acid SCHEMBL28151870 0.77 CA2 (1.00) CA2CA4CA5ACFTRALOX15
SCHEMBL7079874 0.77 CA2 (0.52) CA2CA4CA5ACFTRALOX15
Phenylphosphonic Acid SCHEMBL34998 0.77 CA2 (1.00) CA2CA4CA5ACFTRALOX15
Phenylphosphonic Acid SCHEMBL2790969 0.74 CA2 (0.94) CA2CA4CA5ACFTRALOX15
Phenylphosphonic Acid SCHEMBL20140614 0.74 CA2 (0.94) CA2CA4CA5ACFTRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118179550-A Catalyst for supporting alkali metal and preparation method and application thereof 中国科学院大连化学物理研究所 2024-06-14 CN claimed
CN-109280164-A A kind of coating material and preparation method thereof with ultra-hydrophobicity 南京艾利克斯电子科技有限公司 2019-01-29 CN claimed
CN-109212404-A A kind of remittance energy maintainability test instrument 南京艾利克斯电子科技有限公司 2019-01-15 CN claimed
CN-109159656-A A kind of windshield sunshading cover 南京昊铭远科信息科技有限公司 2019-01-08 CN claimed
CN-109030917-A A kind of digital high-voltage electroscope 南京艾利克斯电子科技有限公司 2018-12-18 CN claimed
CN-118179550-A Catalyst for supporting alkali metal and preparation method and application thereof 中国科学院大连化学物理研究所 2024-06-14 CN disclosed
CN-112334797-B Polarizer and image display device 富士胶片株式会社 2022-12-20 CN disclosed
CN-115136042-A Optical laminate and display device 富士胶片株式会社 2022-09-30 CN disclosed
CN-114502996-A Optical laminate, organic EL display device, and folding device 富士胶片株式会社 2022-05-13 CN disclosed
CN-113490543-A Polymer and method for producing same, gas separation membrane, gas separation module, and gas separation device using same, and m-phenylenediamine compound 富士胶片株式会社 2021-10-08 CN disclosed
US-10905769-B2 Peptide and peptide mimetic binding antagonists of polo-like kinase 1 polo box domain and methods of use THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2021-02-02 US disclosed
CN-110183461-A Cortex chalone analog and its synthesis and purposes 哈佛学院院长等 2019-08-30 CN disclosed
US-6017905-A TREATMENT OF HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS WARNER-LAMBERT COMPANY (US) 2000-01-25 US disclosed
US-5807846-A TREATING HYPERCHOLESTEROLEMIA AND ATHEROSCLEROSIS WARNER-LAMBERT COMPANY (US) 1998-09-15 US disclosed
US-5792444-A ADMINISTERING LABELED CHEMOTACTIC PEPTIDE WHICH ACCUMULATES AT SITE OF INFECTION OR INFLAMMATION THE GENERAL HOSPITAL CORPORATION (US) 1998-08-11 US disclosed
US-4563310-A HERBICIDES ZOECON CORPORATION (US) 1986-01-07 US disclosed
US-4520197-A Tetrahydrobenzodiazaphosphorindiones and tetrahydropyridodiazaphosphorindiones ZOECON CORPORATION (US) 1985-05-28 US disclosed
US-4433149-A Esters of ureido-phenyl (or pyridyl) phosphinic acids ZOECON CORPORATION (US) 1984-02-21 US disclosed
EP-0065374-A1 Substituted phosphinates and phosphinothioates and their use for the control of weeds ZOECON CORPORATION (US) 1982-11-24 EP disclosed
US-3933864-A Process for preparing glycidonitriles THE UPJOHN COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10905769-B2 Peptide and peptide mimetic binding antagonists of polo-like kinase 1 polo box domain and methods of use PLK1, POLR1E, POLK CA2 4383/4885CA4 4674/4885CA5A 3709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.