Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 6/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650928 | 0.98 | SERPINE1 (0.55) | NPC1MAPTRAB9AALDH1A1SERPINE1 | |
| SCHEMBL31634606 | 0.93 | NPC1 (0.51) | NPC1MAPTRAB9AALDH1A1SERPINE1 | |
| SCHEMBL1553600 | 0.91 | ALDH1A1 (0.71) | NPC1MAPTRAB9AALDH1A1ESR1 | |
| SCHEMBL866307 | 0.91 | ALDH1A1 (0.71) | NPC1MAPTRAB9AALDH1A1ESR1 | |
| SCHEMBL29023764 | 0.91 | ALDH1A1 (0.71) | NPC1MAPTRAB9AALDH1A1ESR1 | |
| SCHEMBL1554567 | 0.91 | ALDH1A1 (0.71) | NPC1MAPTRAB9AALDH1A1ESR1 | |
| SCHEMBL1553249 | 0.91 | ALDH1A1 (0.71) | NPC1MAPTRAB9AALDH1A1ESR1 | |
| SCHEMBL3628916 | 0.91 | ALDH1A1 (0.71) | NPC1MAPTRAB9AALDH1A1ESR1 | |
| SCHEMBL9635703 | 0.91 | ALDH1A1 (0.71) | NPC1MAPTRAB9AALDH1A1ESR1 | |
| SCHEMBL1553721 | 0.91 | ALDH1A1 (0.71) | NPC1MAPTRAB9AALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491752-B2 | Photoactive materials | ROLIC AG (CH) | 2009-02-17 | — | — | US | disclosed |
| US-20040265742-A1 | Photoactive materials | ROLIC AG (CH) | 2004-12-30 | — | — | US | disclosed |
| EP-1409563-A1 | PHOTOACTIVE MATERIALS | Rolic AG (CH) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003008472-A1 | PHOTOACTIVE MATERIALS | ROLIC AG (CH) | 2003-01-30 | — | — | WO | disclosed |
| EP-1277770-A1 | Photoactive materials | Rolic AG (CH) | 2003-01-22 | — | — | EP | disclosed |