SCHEMBL4430894

SCHEMBL4430894

O=P(Oc1ccccc1F)(Oc1ccccc1F)Oc1ccccc1F

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
HTT P42858 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
NPSR1 Q6W5P4 2/20 0.47
GAA P10253 2/20 0.47
MAPT P10636 1/20 0.47
XBP1 P17861 1/20 0.47
MAPK1 P28482 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
KDM4E B2RXH2 2/20 0.45
POLB P06746 1/20 0.45
NPC1 O15118 2/20 0.42
ALDH1A1 P00352 1/20 0.39
ESR1 P03372 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1009274 0.89 LMNA (0.47) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL6009761 0.87 LMNA (0.46) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL31306469 0.87 LMNA (0.50) LMNACYP1A2CYP3A4CYP2D6CYP2C9
Nitrogen SCHEMBL28055525 0.84 HTT (0.48) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL1009273 0.84 LMNA (0.50) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL4946769 0.84 LMNA (0.50) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL1471615 0.82 LMNA (0.46) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL1009703 0.82 LMNA (0.43) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL778462 0.82 LMNA (0.53) LMNACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL8519273 0.82 LMNA (0.49) LMNACYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111116659-A Compound, electrolyte and lithium ion battery 张家港市国泰华荣化工新材料有限公司 2020-05-08 CN disclosed
EP-2097428-A2 BUTYRYLCHOLINESTERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES Mgp Biotechnologies, Inc. (US) 2009-09-09 EP disclosed
WO-2008055249-A2 BUTYRYLCHOLINESTERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES MGP BIOTECHNOLOGIES, INC. (US) 2008-05-08 WO disclosed
US-6846542-B1 UV treatment for improving performance of lubricated thin film recording media and media obtained thereby SEAGATE TECHNOLOGY LLC (US) 2005-01-25 US disclosed