Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 8/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PEPD | P12955 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.45 |
| ▸ | FAP | Q12884 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4431061 | 1.00 | FKBP1A (0.56) | FKBP1APOLBLMNARAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31733698 | 0.98 | FKBP1A (0.55) | FKBP1APOLBLMNARAB9ASMN1; SMN2 | |
| SCHEMBL852542 | 0.95 | POLB (0.52) | FKBP1APOLBLMNARAB9ASMN1; SMN2 | |
| SCHEMBL852541 | 0.95 | POLB (0.52) | FKBP1APOLBLMNARAB9ASMN1; SMN2 | |
| SCHEMBL4437850 | 0.95 | POLB (0.52) | FKBP1APOLBLMNARAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7270483 | 0.94 | POLB (0.51) | FKBP1APOLBLMNARAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7271886 | 0.94 | POLB (0.51) | FKBP1APOLBLMNARAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4437853 | 0.94 | POLB (0.51) | FKBP1APOLBLMNARAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4437845 | 0.94 | POLB (0.51) | FKBP1APOLBLMNARAB9ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL4431133 | 0.90 | FKBP1A (0.51) | FKBP1APOLBLMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10711036-B2 | MALT1 inhibitors and uses thereof | CORNELL UNIVERSITY (US) | 2020-07-14 | — | — | US | disclosed |
| US-20130012485-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2013-01-10 | — | — | US | disclosed |
| EP-2124913-A1 | 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS | Novartis AG (CH) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008077597-A1 | 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012485-A1 | ORGANIC COMPOUNDS | DPP4, DPP3, DPP7 | FKBP1A 3050/4885POLB 2463/4885LMNA 4502/4885 |
| US-10711036-B2 | MALT1 inhibitors and uses thereof | MALT1, BCL3, BCL6 | FKBP1A 163/4885POLB 4659/4885LMNA 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.