SCHEMBL443150

SCHEMBL443150

C=C(CCCCc1ccccc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.63
RXFP1 Q9HBX9 1/20 0.63
HDAC1 Q13547 6/20 0.57
HDAC2 Q92769 4/20 0.57
HDAC3 O15379 3/20 0.57
HDAC8 Q9BY41 3/20 0.57
HDAC6 Q9UBN7 3/20 0.57
HDAC5 Q9UQL6 3/20 0.57
HDAC4 P56524 2/20 0.57
HDAC7 Q8WUI4 2/20 0.57
HDAC10 Q969S8 2/20 0.57
HDAC11 Q96DB2 2/20 0.57
HDAC9 Q9UKV0 2/20 0.57
MAPK1 P28482 1/20 0.57
ADRA1A P35348 1/20 0.57
SLC6A3 Q01959 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
ALOX5 P09917 3/20 0.56
FAAH O00519 3/20 0.54
CES1 P23141 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6666636 0.98 MAPT (0.67) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL6255795 0.98 MAPT (0.67) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL625288 0.98 MAPT (0.67) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL343139 0.98 MAPT (0.67) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL445600 0.98 MAPT (0.67) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL626409 0.98 MAPT (0.67) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL8971314 0.98 MAPT (0.67) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL1122041 0.98 MAPT (0.67) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL114130 0.94 HDAC1 (0.64) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL4666437 0.94 HDAC1 (0.64) MAPTRXFP1HDAC1HDAC2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 341 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
EP-3728339-B1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS AMO Ireland (IE) 2022-07-06 EP claimed
US-11242461-B2 Grease, oil, and water resistant coating compositions SUN CHEMICAL CORPORATION (US) 2022-02-08 US claimed
EP-2303331-B1 OPHTHALMIC DEVICE HAVING THERAPEUTIC AGENT DELIVERY CAPABILITY AND METHOD OF FORMING SAME ALCON INC (CH) 2022-01-26 EP claimed
EP-3200840-B1 LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES ALCON INC (CH) 2021-11-17 EP claimed
EP-3368600-B1 WATER-BASED COATING COMPOSITIONS SUN CHEMICAL CORP (US) 2020-06-10 EP claimed
EP-3494186-B1 INKJET INK COMPOSITION HEWLETT PACKARD DEVELOPMENT CO (US) 2020-04-15 EP claimed
US-20200056052-A1 GREASE, OIL, AND WATER RESISTANT COATING COMPOSITIONS SUN CHEMICAL CORPORATION (US) 2020-02-20 US claimed
EP-3200839-B1 HYDROPHOBIC ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES NOVARTIS AG (CH) 2019-09-04 EP claimed
EP-3532677-A1 GREASE, OIL, AND WATER RESISTANT COATING COMPOSITIONS Sun Chemical Corporation (US) 2019-09-04 EP claimed
EP-1071482-B1 INTRAOCULAR LENS COATING COMPOSITIONS ALCON LAB INC (US) 2001-10-04 EP claimed
US-6271281-B1 INTRAOCULAR LENSE OF ACRYLATE POLYMERS MEDENNIUM, INC. 2001-08-07 US claimed
EP-0640672-B1 Anaerobically-curable flexible sealant compositions LOCTITE IRELAND LTD (IE) 1998-03-11 EP claimed
EP-0639590-B1 Process for preparing monodispersed poly (meth)acrylate particles ROEHM GMBH (DE) 1997-02-26 EP claimed
EP-0589340-B1 Urea-modified copolymers as dispersants for pigments in coating compositions BASF CORP (US) 1996-03-06 EP claimed
EP-0639590-A2 Process for preparing monodispersed poly (meth)acrylate particles RÖHM GMBH (DE) 1995-02-22 EP claimed
EP-0312120-B1 PROCESS FOR PREPARING MOULDING MATERIALS OF ACRYLIC RESINS WITH SLIGHT WATER ABSORPTION RÖHM GMBH (DE) 1992-03-04 EP claimed
EP-0115066-B1 MOULDING MATERIAL BASED ON ACRYLIC RESINS WITH SLIGHT WATER ABSORPTION RÖHM GMBH (DE) 1991-08-28 EP claimed
EP-0079057-B1 PRESENSITIZED LITHOGRAPHIC PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1985-09-11 EP claimed
EP-0115066-A2 Moulding Material based on acrylic resins with slight water absorption Röhm GmbH (DE) 1984-08-08 EP claimed