Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.64 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.64 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.64 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.64 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.64 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.64 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114130 | 1.00 | HDAC1 (0.64) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL11273048 | 0.98 | HDAC1 (0.62) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL17940810 | 0.96 | HDAC1 (0.60) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL443150 | 0.94 | MAPT (0.63) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL444700 | 0.93 | HDAC1 (0.56) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL8971314 | 0.92 | MAPT (0.67) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL6666636 | 0.92 | MAPT (0.67) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL343139 | 0.92 | MAPT (0.67) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL626409 | 0.92 | MAPT (0.67) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL445600 | 0.92 | MAPT (0.67) | HDAC1HDAC2HDAC3HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208393-B1 | COVALENTLY-BOUND, HYDROPHILIC COATING COMPOSITIONS FOR IMPLANTS | ALCON INC (CH) | 2008-10-08 | — | — | EP | claimed |
| EP-1207808-B1 | HYDROPHOBICALLY-BOUND, HYDROPHILIC COATING COMPOSITIONS FOR SURGICAL IMPLANTS | ALCON INC (CH) | 2005-01-12 | — | — | EP | claimed |