SCHEMBL443151

SCHEMBL443151

CC(=CCCCc1ccccc1)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 3/20 0.48
HDAC1 Q13547 3/20 0.48
HDAC2 Q92769 3/20 0.48
HDAC8 Q9BY41 3/20 0.48
HDAC6 Q9UBN7 3/20 0.48
HDAC5 Q9UQL6 3/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
ALDH1A1 P00352 3/20 0.48
HDAC4 P56524 2/20 0.48
HDAC7 Q8WUI4 2/20 0.48
HDAC10 Q969S8 2/20 0.48
HDAC11 Q96DB2 2/20 0.48
HDAC9 Q9UKV0 2/20 0.48
MAPK1 P28482 1/20 0.48
ADRA1A P35348 1/20 0.48
SLC6A3 Q01959 1/20 0.48
TBXAS1 P24557 1/20 0.48
CYP2C9 P11712 2/20 0.46
MAPT P10636 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1574137 1.00 HDAC3 (0.48) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL4667862 1.00 HDAC3 (0.48) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL445601 0.95 TBXAS1 (0.50) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL813333 0.95 TBXAS1 (0.50) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL6255796 0.93 TBXAS1 (0.52) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL1122044 0.93 TBXAS1 (0.52) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL343141 0.93 TBXAS1 (0.52) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL6467606 0.93 TBXAS1 (0.52) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL1122039 0.93 TBXAS1 (0.52) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL2967192 0.93 TBXAS1 (0.52) HDAC3HDAC1HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250326877-A1 DIACRYLATED MONOLIGNOL THERMOSET RESINS VITO NV (BE) 2025-10-23 US claimed
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
WO-2023111349-A1 DIACRYLATED MONOLIGNOL THERMOSET RESINS VITO NV (BE) 2023-06-22 WO claimed
EP-4198065-A1 DIACRYLATED MONOLIGNOL THERMOSET RESINS Vito NV (BE) 2023-06-21 EP claimed
EP-3728339-B1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS AMO Ireland (IE) 2022-07-06 EP claimed
US-11242461-B2 Grease, oil, and water resistant coating compositions SUN CHEMICAL CORPORATION (US) 2022-02-08 US claimed
EP-2303331-B1 OPHTHALMIC DEVICE HAVING THERAPEUTIC AGENT DELIVERY CAPABILITY AND METHOD OF FORMING SAME ALCON INC (CH) 2022-01-26 EP claimed
EP-3200840-B1 LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES ALCON INC (CH) 2021-11-17 EP claimed
WO-2021121889-A1 DCA METHACRYLATE THERMOPLASTIC POLYMERS VITO NV (BE) 2021-06-24 WO claimed
EP-3494186-B1 INKJET INK COMPOSITION HEWLETT PACKARD DEVELOPMENT CO (US) 2020-04-15 EP claimed
EP-0914169-B1 MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES ALCON LAB INC (US) 2003-07-30 EP claimed
EP-0661357-B1 Polymeric pigment dispersants for use in coating compositions BASF CORP (US) 2001-10-31 EP claimed
EP-0640672-B1 Anaerobically-curable flexible sealant compositions LOCTITE IRELAND LTD (IE) 1998-03-11 EP claimed
EP-0639590-B1 Process for preparing monodispersed poly (meth)acrylate particles ROEHM GMBH (DE) 1997-02-26 EP claimed
EP-0589340-B1 Urea-modified copolymers as dispersants for pigments in coating compositions BASF CORP (US) 1996-03-06 EP claimed
EP-0639590-A2 Process for preparing monodispersed poly (meth)acrylate particles RÖHM GMBH (DE) 1995-02-22 EP claimed
EP-0312120-B1 PROCESS FOR PREPARING MOULDING MATERIALS OF ACRYLIC RESINS WITH SLIGHT WATER ABSORPTION RÖHM GMBH (DE) 1992-03-04 EP claimed
EP-0115066-B1 MOULDING MATERIAL BASED ON ACRYLIC RESINS WITH SLIGHT WATER ABSORPTION RÖHM GMBH (DE) 1991-08-28 EP claimed
EP-0079057-B1 PRESENSITIZED LITHOGRAPHIC PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1985-09-11 EP claimed
EP-0115066-A2 Moulding Material based on acrylic resins with slight water absorption Röhm GmbH (DE) 1984-08-08 EP claimed