Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bambuterol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 1.00 |
| ▸ | BCHE | P06276 | 6/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | ACHE | P22303 | 2/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bambuterol SCHEMBL4431 | 1.00 | BCHE (1.00) | BCHECYP2D6ACHEADRB2KCNH2 | |
| Bambuterol SCHEMBL13923751 | 1.00 | BCHE (1.00) | BCHECYP2D6ACHEADRB2KCNH2 | |
| Bambuterol SCHEMBL744580 | 0.99 | BCHE (0.97) | BCHECYP2D6ACHEADRB2KCNH2 | |
| Bambuterol SCHEMBL1649102 | 0.97 | BCHE (0.95) | BCHECYP2D6ACHEADRB2KCNH2 | |
| Bambuterol SCHEMBL3713500 | 0.96 | BCHE (0.92) | BCHECYP2D6ACHEADRB2KCNH2 | |
| SCHEMBL15790253 | 0.95 | BCHE (0.90) | BCHECYP2D6ACHEADRB2KCNH2 | |
| Bambuterol SCHEMBL21645369 | 0.95 | BCHE (0.90) | BCHECYP2D6ACHEADRB2KCNH2 | |
| SCHEMBL21674420 | 0.93 | BCHE (0.88) | BCHECYP2D6ACHEADRB2KCNH2 | |
| Hydrochloric Acid SCHEMBL11123610 | 0.92 | BCHE (0.85) | BCHECYP2D6ACHEADRB2KCNH2 | |
| SCHEMBL15790471 | 0.92 | BCHE (0.85) | BCHECYP2D6ACHEADRB2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 11298 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260132115-A1 | SUBSTITUTED 3-FLUOROBENZENEPROPANOATE COMPOUND AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | TIANJIN GUDUI BIO PHARM CO LTD (CN) | 2026-05-14 | — | — | US | claimed |
| EP-4739295-A1 | AN INHALABLE FORMULATION OF FLUTICASONE PROPIONATE AND ALBUTEROL SULFATE FOR THE TREATMENT OF ASTHMA | Norton (Waterford) Limited (IE) | 2026-05-13 | — | — | EP | claimed |
| EP-4739294-A1 | AN INHALABLE FORMULATION OF FLUTICASONE PROPIONATE AND ALBUTEROL SULFATE FOR THE TREATMENT OF ASTHMA | Norton (Waterford) Limited (IE) | 2026-05-13 | — | — | EP | claimed |
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| EP-4434588-B1 | AEROSOL DELIVERY DEVICE | PARI PHARMA GMBH (DE) | 2026-04-08 | — | — | EP | claimed |
| EP-4722714-A1 | SIMULTANEOUS ANALYSIS OF FOOD-BORNE DOPING SUBSTANCES USING LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY (VFD: VACCINE FOR FOODBORNE DOPING) | Korea Institute of Science and Technology (KR) | 2026-04-08 | — | — | EP | claimed |
| US-20260021124-A1 | BUDESONIDE 21-PHOSPHATE SALTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | GENETIC S P A (IT) | 2026-01-22 | — | — | US | claimed |
| EP-4678170-A1 | A FIXED-DOSE DRY POWDER INHALATION FORMULATION OF FLUTICASONE PROPIONATE AND ALBUTEROL SULFATE FOR THE TREATMENT OF ASTHMA | Norton (Waterford) Limited (IE) | 2026-01-14 | — | — | EP | claimed |
| EP-4649960-A1 | USE OF LONG-ACTING ß2AR AGONIST IN PREPARATION OF DRUGS FOR TREATING CANCERS | Hong Kong Sxmeterol Pharmaceutical Co., Limited (HK) | 2025-11-19 | — | — | EP | claimed |
| EP-4642463-A1 | PHARMACEUTICAL COMPOSITIONS OF GREEN PROPELLANT | Cipla Limited (IN) | 2025-11-05 | — | — | EP | claimed |
| EP-0580648-B1 | PROCESS FOR CONDITIONING OF WATER-SOLUBLE SUBSTANCES | ASTRA AB (SE) | 1996-05-08 | — | — | EP | claimed |
| WO-1995005805-A1 | PROCESS FOR CONDITIONING SUBSTANCES | ASTRA AKTIEBOLAG (SE) | 1995-03-02 | — | — | WO | claimed |
| EP-0521967-A1 | NEW USE OF BAMBUTEROL. | ASTRA AB (SE) | 1993-01-13 | — | — | EP | claimed |
| EP-0514415-A1 | NOVEL VEHICLE GAS MIXTURES AND THEIR USE IN MEDICAL PREPARATIONS | BOEHRINGER INGELHEIM KG (DE) | 1992-11-25 | — | — | EP | claimed |
| EP-0513099-A1 | NOVEL VEHICLE GASES AND THEIR USE IN MEDICAL PREPARATIONS | BOEHRINGER INGELHEIM KG (DE) | 1992-11-19 | — | — | EP | claimed |
| EP-0508969-A1 | Process for conditioning of water-soluble substances | Astra Aktiebolag (SE) | 1992-10-14 | — | — | EP | claimed |
| WO-1991013615-A1 | NEW USE OF BAMBUTEROL | AKTIEBOLAGET ASTRA (SE) | 1991-09-19 | — | — | WO | claimed |
| WO-1991011495-A1 | NOVEL VEHICLE GAS MIXTURES AND THEIR USE IN MEDICAL PREPARATIONS | BOEHRINGER INGELHEIM KG (DE) | 1991-08-08 | — | — | WO | claimed |
| WO-1991011496-A1 | NOVEL VEHICLE GASES AND THEIR USE IN MEDICAL PREPARATIONS | BOEHRINGER INGELHEIM KG (DE) | 1991-08-08 | — | — | WO | claimed |
| EP-0341559-A2 | Synergistic mixtures and their therapeutical use | BOEHRINGER INGELHEIM KG (DE) | 1989-11-15 | — | — | EP | claimed |