Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | BID | P55957 | 3/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.33 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6558282 | 0.93 | LIPG (0.47) | LIPGCYP3A4TYRALOX5PTGS2 | |
| SCHEMBL10661020 | 0.93 | LIPG (0.47) | LIPGCYP3A4TYRALOX5PTGS2 | |
| SCHEMBL9322497 | 0.88 | PPARG (0.32) | PPARGPPARA | |
| SCHEMBL456598 | 0.79 | — | — | |
| SCHEMBL2972730 | 0.78 | LIPG (0.39) | CTRCLIPGCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL677297 | 0.78 | LIPG (0.39) | CTRCLIPGCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7828514 | 0.77 | LIPG (0.38) | CTRCLIPGCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3684256 | 0.77 | TLR8 (0.40) | LIPGCYP3A4CYP2D6CYP2C9TYR | |
| SCHEMBL919936 | 0.77 | TYR (0.39) | CTRCLIPGCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6222948 | 0.77 | TYR (0.43) | LIPGCYP3A4CYP2D6CYP2C9TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097428-A2 | BUTYRYLCHOLINESTERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Mgp Biotechnologies, Inc. (US) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008055249-A2 | BUTYRYLCHOLINESTERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | MGP BIOTECHNOLOGIES, INC. (US) | 2008-05-08 | — | — | WO | disclosed |
| WO-1993023398-A1 | SUBSTITUTED PYRIDO[1,2-A]PYRIMIDINONE DERIVATIVES AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-11-25 | — | — | WO | disclosed |