Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA9 | Q16790 | 4/20 | 0.38 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249309 | 0.76 | KDM4E (0.33) | ALDH1A1KDM4ECA1CA12CA9 | |
| SCHEMBL6578197 | 0.73 | CA12 (0.36) | ALDH1A1HSD17B10CYP2D6CA1CA12 | |
| SCHEMBL27262586 | 0.72 | SELL (0.57) | ALDH1A1KDM4EHSD17B10HPGDCYP2D6 | |
| SCHEMBL896338 | 0.71 | CA12 (0.36) | ALDH1A1HSD17B10CA1CA12CA9 | |
| SCHEMBL1832044 | 0.71 | ALB (0.43) | ALDH1A1KDM4ECA1CA12CA9 | |
| SCHEMBL1834310 | 0.71 | CA12 (0.41) | ALDH1A1KDM4EHSD17B10HPGDCA1 | |
| SCHEMBL27653713 | 0.71 | SELL (0.55) | ALDH1A1KDM4EHSD17B10HPGDCYP2D6 | |
| SCHEMBL16767652 | 0.70 | ERN1 (0.33) | CA1CA12CA9CA2 | |
| SCHEMBL27572751 | 0.69 | SELL (0.48) | ALDH1A1KDM4EHSD17B10HPGDCYP2D6 | |
| SCHEMBL20837977 | 0.69 | CA12 (0.42) | ALDH1A1KDM4EHSD17B10HPGDCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632816-B2 | Treatment of Alzheimer amyloid deposition | NEW YORK UNIVERSITY (US) | 2009-12-15 | — | — | US | disclosed |
| US-20040214774-A1 | Prevention and treatment of Alzheimer amyloid deposition | NEW YORK UNIVERSITY | 2004-10-28 | — | — | US | disclosed |