Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12880594 | 0.86 | TSHR (0.32) | TSHR | |
| SCHEMBL4076454 | 0.82 | TSHR (0.48) | TSHRDPP4F2SLC6A2SLC6A4 | |
| SCHEMBL4086098 | 0.82 | TSHR (0.48) | TSHRDPP4F2SLC6A2SLC6A4 | |
| SCHEMBL9085359 | 0.78 | TSHR (0.44) | TSHRDPP4F2SLC6A2SLC6A4 | |
| SCHEMBL29262216 | 0.77 | CHRNA7 (0.41) | SLC6A3GAAALDH1A1HTTLMNA | |
| SCHEMBL4077859 | 0.76 | TSHR (0.52) | TSHRDPP4F2SLC6A2SLC6A4 | |
| SCHEMBL11562135 | 0.75 | TSHR (0.41) | TSHRDPP4F2SLC6A2SLC6A4 | |
| SCHEMBL8760763 | 0.73 | TSHR (0.44) | TSHRDPP4F2SLC6A2SLC6A4 | |
| SCHEMBL4310847 | 0.73 | TSHR (0.44) | TSHRDPP4F2SLC6A2SLC6A4 | |
| SCHEMBL8463740 | 0.72 | DPP4 (0.41) | TSHRDPP4F2SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032624-A1 | WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION | Sabic Innovative Plastics IP B.V. (NL) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008002757-A1 | WEATHERABLE, THERMOSTABLE POLYMERS HAVING IMPROVED FLOW COMPOSITION | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2008-01-03 | — | — | WO | disclosed |