SCHEMBL4086098

SCHEMBL4086098

C[Si](C)(Cl)C(Cl)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
DPP4 P27487 2/20 0.36
F2 P00734 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
AOC3 Q16853 1/20 0.35
GAA P10253 1/20 0.35
TAAR1 Q96RJ0 2/20 0.34
HTR2A P28223 1/20 0.34
HRH1 P35367 1/20 0.34
LMNA P02545 1/20 0.34
ADRA2A P08913 1/20 0.33
ADRA2C P18825 1/20 0.33
CYP2D6 P10635 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4076454 0.85 TSHR (0.48) TSHRDPP4F2SLC6A2SLC6A4
SCHEMBL4432993 0.82 TSHR (0.50) TSHRDPP4F2SLC6A2SLC6A4
SCHEMBL4077859 0.79 TSHR (0.52) TSHRDPP4F2SLC6A2SLC6A4
SCHEMBL9085359 0.76 TSHR (0.44) TSHRDPP4F2SLC6A2SLC6A4
SCHEMBL3799465 0.75 ADRA2A (0.43) TSHRDPP4F2SLC6A2SLC6A4
SCHEMBL11562135 0.73 TSHR (0.41) TSHRDPP4F2SLC6A2SLC6A4
SCHEMBL6671378 0.72 TSHR (0.43) TSHRDPP4F2SLC6A2SLC6A4
SCHEMBL4310847 0.71 TSHR (0.44) TSHRDPP4F2SLC6A2SLC6A4
SCHEMBL8760763 0.71 TSHR (0.44) TSHRDPP4F2SLC6A2SLC6A4
SCHEMBL523287 0.70 LMNA (0.45) TSHRAOC3TAAR1HTR2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705207-B1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR CORP (JP) 2012-10-24 EP disclosed
US-7528207-B2 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070021580-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-25 US disclosed
US-20070015892-A1 Method for producing polymer, polymer, composition for forming insulating film, method for producing insulating film, and insulating film JSR CORPORATION (JP) 2007-01-18 US disclosed
EP-1705206-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed
EP-1705207-A1 METHOD FOR PRODUCING POLYMER, POLYMER, COMPOSITION FOR FORMING INSULATING FILM, METHOD FOR PRODUCING INSULATING FILM, AND INSULATING FILM JSR Corporation (JP) 2006-09-27 EP disclosed