Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | BCL9 | O00512 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3335231 | 0.78 | MGLL (0.50) | MGLLTHRBTP53BCL9CTNNB1 | |
| SCHEMBL25381206 | 0.77 | MGLL (0.56) | MGLLTHRBTP53BCL9CTNNB1 | |
| SCHEMBL22370754 | 0.75 | MGLL (0.47) | MGLLTHRBTP53BCL9CTNNB1 | |
| SCHEMBL31414907 | 0.74 | MGLL (0.56) | MGLLTHRBBCL9CTNNB1GAA | |
| SCHEMBL31414904 | 0.74 | MGLL (0.53) | MGLLTHRBTP53BCL9CTNNB1 | |
| SCHEMBL29716297 | 0.73 | BCL9 (0.51) | MGLLTHRBBCL9CTNNB1LMNA | |
| 4-Nitrophenyl Ethylcarbamate SCHEMBL1695035 | 0.73 | MGLL (0.74) | MGLLBCL9CTNNB1GAAFAAH | |
| SCHEMBL18703462 | 0.73 | MGLL (0.78) | MGLLBCL9CTNNB1GAAFAAH | |
| SCHEMBL27709773 | 0.72 | MGLL (0.54) | MGLLTHRBTP53BCL9CTNNB1 | |
| SCHEMBL15232603 | 0.71 | MGLL (0.71) | MGLLBCL9CTNNB1GAAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101631768-A | Novel prodrugs | SUN PHARMA ADVANCED RES CO LTD | 2010-01-20 | — | — | CN | disclosed |
| EP-2118052-A2 | NOVEL PRODRUGS | Sun Pharma Advanced Research Company Ltd (IN) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008111096-A2 | NOVEL PRODRUGS | SUN PHARMA ADVANCED RESEARCH COMPANY LTD (IN) | 2008-09-18 | — | — | WO | disclosed |