⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27411081 | 0.90 | — | — | |
| SCHEMBL27410894 | 0.84 | — | — | |
| SCHEMBL4427951 | 0.84 | — | — | |
| SCHEMBL4433263 | 0.84 | POLB (0.41) | — | |
| SCHEMBL4424342 | 0.83 | MAPT (0.41) | — | |
| SCHEMBL4425759 | 0.82 | POLB (0.51) | — | |
| SCHEMBL4433277 | 0.81 | CA12 (0.40) | — | |
| SCHEMBL4422683 | 0.81 | CCNT1 (0.44) | — | |
| SCHEMBL4434995 | 0.80 | MAPT (0.44) | — | |
| SCHEMBL27411894 | 0.80 | POLB (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217997-A1 | NOVEL MEPICIDES AS ANTIMICROBIAL AGENTS | GEORGE MASON UNIVERSITY | 2024-07-04 | — | — | US | disclosed |
| US-20240217997-A1 | NOVEL MEPICIDES AS ANTIMICROBIAL AGENTS | GEORGE MASON UNIVERSITY | 2024-07-04 | — | — | US | disclosed |
| US-7638505-B2 | Organophosphoric derivatives useful as anti-parasitic agents | UNIVERSITEIT GENT (BE) | 2009-12-29 | — | — | US | disclosed |
| US-20080312190-A1 | Such as 3-(N-hydroxyacetamido)-1-(3,4-dichlorophenyl)propylphosphonic acid; Antimalaria agents | UNIVERSITEIT GENT (BE) | 2008-12-18 | — | — | US | disclosed |