Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.50 |
| ▸ | CHRNG | P07510 | 2/20 | 0.50 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.50 |
| ▸ | CHRND | Q07001 | 2/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12313096 | 1.00 | SLC6A3 (0.61) | SLC6A3SLC6A4SLC6A2CHRNB2CHRNA4 | |
| SCHEMBL13227345 | 1.00 | SLC6A3 (0.61) | SLC6A3SLC6A4SLC6A2CHRNB2CHRNA4 | |
| SCHEMBL2640060 | 1.00 | SLC6A3 (0.61) | SLC6A3SLC6A4SLC6A2CHRNB2CHRNA4 | |
| SCHEMBL3587139 | 1.00 | SLC6A3 (0.61) | SLC6A3SLC6A4SLC6A2CHRNB2CHRNA4 | |
| SCHEMBL13255979 | 0.90 | SLC6A3 (0.62) | SLC6A3SLC6A4SLC6A2CHRNB2CHRNA4 | |
| Cadaverine Tartrate SCHEMBL2639730 | 0.89 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2CHRNB2CHRNA4 | |
| Cadaverine Tartrate SCHEMBL3553053 | 0.89 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2CHRNB2CHRNA4 | |
| Cadaverine Tartrate SCHEMBL6013535 | 0.89 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2CHRNB2CHRNA4 | |
| Cadaverine Tartrate SCHEMBL2639906 | 0.89 | SLC6A3 (0.58) | SLC6A3SLC6A4SLC6A2CHRNB2CHRNA4 | |
| SCHEMBL1984900 | 0.88 | SLC6A3 (0.57) | SLC6A3SLC6A4SLC6A2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132205-A1 | HYDROCHLORIDE SALT OF AN AZABICYCLO[3.2.1]OCTANE DERIVATIVE | NEUROSEARCH A/S (DK) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008104584-A1 | HYDROCHLORIDE SALT OF AN AZABICYCLO[3.2.1]OCTANE DERIVATIVE | GLAXO GROUP LIMITED (GB) | 2008-09-04 | — | — | WO | disclosed |